ArticleCritical care (London, England)2018
Enteral nutrition feeding in Chinese intensive care units: a cross-sectional study involving 116 hospitals.
Article in Critical care (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Energy-dense versus routine enteral nutrition in critically ill patients: a systematic review and meta-analysis.Frontiers in nutrition · 2025Pooled it
- Actively implementing an evidence-based feeding guideline for critically ill patients (NEED): a multicenter, cluster-randomized, controlled trial.Critical care (London, England) · 2022Trial
- Trial
- Enhanced metabolic regulation in II/R injury: Comparing multiroute and monoroute enteral nutrition.JPEN. Journal of parenteral and enteral nutrition · 2025Article
- Comparison of standard polymer formula versus short peptide formula in sepsis patients with acute gastrointestinal injury.Frontiers in nutrition · 2025Article
- Barriers to timely nutritional intervention in ICU patients: exploring predictive factors and neuroendocrine regulatory pathways.Frontiers in nutrition · 2025Article
- Protective nutrition strategy in the acute phase of critical illness: why, what and how to protect.Frontiers in nutrition · 2025Review
- Nutritional practices and impact of feeding adequacy on clinical outcomes in Chinese respiratory intensive care units patients: a prospective observational study (ORIENT study).Frontiers in nutrition · 2025Article
- Semi-elemental versus polymeric formula for enteral nutrition in critically ill patients: a secondary analysis of a multicenter cluster-randomized controlled trial.Frontiers in nutrition · 2025Article
- The effect of early intravenous amino acid supplementation in critically ill patients without acute kidney injury: Protocol for a multicentre, randomised, parallel-controlled trial (the ESSENTIAL trial).Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2024Article
- Trajectories of acute gastrointestinal injury grade in critically Ill children.BMC pediatrics · 2024Article
- Research and exploration of quality control indicators for nutritional therapy in critically ill patients-a multicenter before-and-after controlled study.Frontiers in nutrition · 2024Article
- The mode and timing of administrating nutritional treatment of critically ill elderly patients in intensive care units: a multicenter prospective study.Frontiers in medicine · 2024Article
- Improving enteral nutrition tolerance and protein intake maybe beneficial to intensive care unit patients.Scientific reports · 2023Article
- Optimizing enteral nutrition delivery by implementing volume-based feeding protocol for critically ill patients: an updated meta-analysis and systematic review.Critical care (London, England) · 2023Review
- Association between Domperidone Administered via Feeding Tube and Feeding Success in Critically Ill Patients with Enteral Feeding Intolerance.Journal of personalized medicine · 2021Article
- Novel Multiparametric Nomogram for Overall Survival Prediction in Complicated Intra-Abdominal Infection: A Multicenter Study in China.Frontiers in medicine · 2021Article
- How to improve worldwide early enteral nutrition performance in intensive care units?Critical care (London, England) · 2018Article
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120 authors.
Funding
Abstract
backgroundThere is a lack of large-scale epidemiological data on the clinical practice of enteral nutrition (EN) feeding in China. This study aimed to provide such data on Chinese hospitals and to investigate factors associated with EN delivery.
methodsThis cross-sectional study was launched in 118 intensive care units (ICUs) of 116 mainland hospitals and conducted on April 26, 2017. At 00:00 on April 26, all patients in these ICUs were included. Demographic and clinical variables of patients on April 25 were obtained. The dates of hospitalization, ICU admission and nutrition initiation were reviewed. The outcome status 28 days after the day of investigation was obtained.
resultsA total of 1953 patients were included for analysis, including 1483 survivors and 312 nonsurvivors. The median study day was day 7 (IQR 2-19 days) after ICU entry. The proportions of subjects starting EN within 24, 48 and 72 h after ICU entry was 24.8% (84/352), 32.7% (150/459) and 40.0% (200/541), respectively. The proportion of subjects receiving > 80% estimated energy target within 24, 48, 72 h and 7 days after ICU entry was 10.5% (37/352), 10.9% (50/459), 11.8% (64/541) and 17.8% (162/910), respectively. Using acute gastrointestinal injury (AGI) 1 as the reference in a Cox model, patients with AGI 2-3 were associated with reduced likelihood of EN initiation (HR 0.46, 95% CI 0.353-0.599; p < 0.001). AGI 4 was significantly associated with lower hazard of EN administration (HR 0.056; 95% CI 0.008-0.398; p = 0.004). In a linear regression model, greater Sequential Organ Failure Assessment scores (coefficient - 0.002, 95% CI - 0.008 to - 0.001; p = 0.024) and male gender (coefficient - 0.144, 95% CI - 0.203 to - 0.085; p < 0.001) were found to be associated with lower EN proportion. As compared with AGI 1, AGI 2-3 was associated with lower EN proportion (coefficient - 0.206, 95% CI - 0.273 to - 0.139; p < 0.001).
conclusionsThe study showed that EN delivery was suboptimal in Chinese ICUs. More attention should be paid to EN use in the early days after ICU admission.
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