ArticleJournal of enzyme inhibition and medicinal chemistry2018
Synthesis and characterisation of (Z)-styrylbenzene derivatives as potential selective anticancer agents.
Article in Journal of enzyme inhibition and medicinal chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
4 citing papers in PubMed, 8 citations in OpenAlex.
- Synthesis and Selective Anticancer Activity Evaluation of 2-phenylacrylonitrile Derivatives as Tubulin Inhibitors.Current medicinal chemistry · 2024Article
- Development of Combretastatin A-4 Analogues as Potential Anticancer Agents with Improved Aqueous Solubility.Molecules (Basel, Switzerland) · 2023Article
- Anticancer sulfonamide hybrids that inhibit bladder cancer cells growth and migration as tubulin polymerisation inhibitors.Journal of enzyme inhibition and medicinal chemistry · 2019Article
- Synthesis of nitrogen mustard-based fluorophores for cell imaging and cytotoxicity studies.Journal of advanced pharmaceutical technology & researchArticle
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To identify anticancer agents with high potency and low toxicity, a series of (Z)-styrylbenzene derivatives were synthesised and evaluated for anticancer activities using a panel of nine cancer cell lines and two noncancerous cell lines. Most derivatives exhibited significant anti-proliferative activities against five cancer cell lines, including MGC-803 and BEL-7402. (Z)-3-(p-Tolyl)-2-(3,4,5-trimethoxyphenyl)acrylonitrile (6h) showed a strong inhibitory effect on MGC-803 cells (IC
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Registered trials
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