ArticleAnnals of surgical oncology2018
Long-Term Survival in Octogenarians After Surgical Treatment for Colorectal Cancer: Prevention of Postoperative Complications is Key.
Article in Annals of surgical oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 63 citations in OpenAlex.
- Evaluation of the safety and efficacy of perform enterectomy in colorectal cancer patients aged 80 or older. A meta-analysis and a systematic review.International journal of colorectal disease · 2023Pooled it
- Low skeletal muscle mass and postoperative morbidity in surgical oncology: a systematic review and meta-analysis.Journal of cachexia, sarcopenia and muscle · 2020Pooled it
- Prognostic value of D3 lymph node dissection and nutritional status in colorectal cancer patients aged 80 years and older.International journal of colorectal disease · 2026Article
- Real-World Results of Curative Open Colorectal Cancer Surgery in Octogenarians: Long-Term Survival Despite High Frailty Burden.Medical sciences (Basel, Switzerland) · 2026Observational
- Age and Colorectal Cancer Outcomes: A Comparative Analysis Between Patients Younger and Older than 70 Years.Current oncology (Toronto, Ont.) · 2026Article
- Elucidating the role of AC026412.3 in hepatocellular carcinoma: a prognostic disulfidptosis-related LncRNAs model perspective.BMC gastroenterology · 2025Article
- Oncologic outcomes of surgically treated colorectal cancer in octogenarians: a comparative study using inverse probability of treatment weighting (IPTW).BMC gastroenterology · 2025Article
- Medical treatment cost for Chinese inpatients with colorectal cancer by sites.Frontiers in public health · 2025Observational
- Association of Preoperative Frailty in Older Taiwanese Patients with Colorectal Cancer.Risk management and healthcare policy · 2025Article
- An internally and externally validated nomogram for predicting cancer-specific survival in octogenarians after radical resection for colorectal cancer.Aging clinical and experimental research · 2024Article
- Enhancing surgical outcomes in elderly gastric cancer patients: the role of comprehensive preoperative assessment and support.World journal of surgical oncology · 2024Article
- Relationship between the m-FI 11 score and 2-year survival in octogenarians undergoing colorectal cancer resection.Annals of medicine and surgery (2012) · 2024Article
- Colorectal cancer surgery in octogenarians: real-world long-term results.Langenbeck's archives of surgery · 2023Review
- Outcomes in octogenarians following elective colorectal cancer surgery.Journal of gastrointestinal oncology · 2023Article
- Surgery for Metastatic Spinal Disease in Octogenarians and Above: Analysis of 78 Patients.Global spine journal · 2023Article
- Clinical outcomes and cost comparison of laparoscopic versus open surgery in elderly colorectal cancer patients over 80 years.International journal of colorectal disease · 2023Article
- Disproportionately high failure to rescue rates after resection for colorectal cancer in the geriatric patient population - A nationwide study.Cancer medicine · 2022Article
- Observational
- Octogenarian patients with colon cancer - postoperative morbidity and mortality are the major challenges.BMC cancer · 2022Article
- Follow-up after emergency laparotomy suggests high one- and five-year mortality with risk stratified by ASA.Annals of the Royal College of Surgeons of England · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhether to treat octogenarians with colorectal cancer (CRC) in the same manner as younger patients remains a challenging issue. The purpose of this study was to analyse postoperative complications and long-term survival in a consecutive cohort of octogenarians who were surgically treated for CRC.
methodsOctogenarians with primary CRC suitable for curative surgery between January 2008 and December 2011 were included. Data about comorbidities, tumour stage, and complications were retrospectively collected from patient files. Data about survival were retrieved with use of the Dutch database for persons and addresses. To identify factors associated with severe postoperative complications and postoperative survival, logistic regression analyses, and Cox regression analyses were performed. Odds ratios and hazard ratios (HR) with 95% confidence intervals (CI) were estimated.
resultsIn a series of 108 octogenarians, median age was 83 years (range 80-94 years). Median follow-up was 47 (range 1-107) months. Major postoperative complications occurred in 25% of the patients. No risk factors for development of severe postoperative complications could be identified. The 30-day mortality was 7%; 1- and 5-year mortality was 19% and 56%, respectively. Overall median survival was 48 months: 66 months in patients without complications versus 13 months in patients with postoperative complications. Postoperative complications were most predictive of decreased survival (HR 3.16; 95% CI 1.79-5.59), even including tumour characteristics, comorbidity, and emergency surgery.
conclusionsLong-term survival in octogenarians deemed fit for surgery is reasonably good. Prevention of major postoperative complications could further improve clinical outcome.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.