ArticleLasers in medical science2019
Wound-healing effects of 635-nm low-level laser therapy on primary human vocal fold epithelial cells: an in vitro study.
Article in Lasers in medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 34 citations in OpenAlex.
- Trial
- Photobiomodulation on vocal training and rehabilitation: Delphi consensus based on experts.CoDAS · 2025Article
- Laryngeal photobiomodulation: application sites, interferences from body mass index and skin phototype.CoDAS · 2024Observational
- Light-Based Therapy: Novel Approach to Treat COVID-19.Tanaffos · 2023Review
- Opinion of speech-language pathologist on the use of photobiomodulation in the vocal clinic.CoDAS · 2023Observational
- Effects of high-frequency near infrared laser irradiation on experimental tooth movement-induced pain in rats.Lasers in medical science · 2022Article
- Article
- Treatment with Light-Emitting Diodes of Wavelength 863 nm Delays DMBA/TPA-Induced Skin Tumor Formation and Decreases Proinflammatory Cytokine Levels in ICR Mice.BioMed research international · 2022Article
- Phonosurgery: A review of current methodologies.World journal of otorhinolaryngology - head and neck surgery · 2021Review
- Photobiomodulation therapy as a high potential treatment modality for COVID-19.Lasers in medical science · 2021Review
- Photobiomodulation With Blue Laser Inhibits Bladder Cancer Progression.Frontiers in oncology · 2021Article
- Protein Substrate Alters Cell Physiology in Primary Culture of Vocal Fold Epithelial Cells.Cells, tissues, organs · 2021Article
- Photobiomodulation increases cell viability via AKT activation in an in vitro model of diabetes induced by glucose neurotoxicity.Lasers in medical science · 2020Article
- Pathophysiology of Fibrosis in the Vocal Fold: Current Research, Future Treatment Strategies, and Obstacles to Restoring Vocal Fold Pliability.International journal of molecular sciences · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
Low-level laser therapy (LLLT) has been promoted for its beneficial effects on tissue healing and pain relief for skin and oral applications. However, there is no corresponding literature reporting on vocal fold wound healing. Our purpose was to assess the potential wound-healing effects of LLLT on primary human vocal fold epithelial cells (VFECs). In this study, normal vocal fold tissue was obtained from a 58-year-old male patient who was diagnosed with postcricoid carcinoma without involvement of the vocal folds and underwent total laryngectomy. Primary VFECs were then cultured. Cells were irradiated at a wavelength of 635 nm with fluences of 1, 4, 8, 12, 16, and 20 J/cm
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.