ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2019
Psychosocial predictors of quality of life among South Africa adolescents receiving antiretroviral therapy.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.
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Who cites it
6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Non-pharmacological interventions for improving sleep in people living with HIV: a systematic narrative review.Frontiers in neurology · 2023Pooled it
- Informing the measurement of wellbeing among young people living with HIV in sub-Saharan Africa for policy evaluations: a mixed-methods systematic review.Health and quality of life outcomes · 2020Pooled it
- Agreement and measurement properties of the interviewer-administered, self-completed and proxy-reported versions of the Tigrinya EQ-5D-Y-5L in Ethiopia.The European journal of health economics : HEPAC : health economics in prevention and care · 2026Article
- Mental Health Problems Across the HIV Care Continuum for Adolescents Living with HIV in Sub-Saharan Africa: A Scoping Review.AIDS and behavior · 2023Article
- Adolescent Girls and Young Women's Experiences of Living with HIV in the Context of Patriarchal Culture in Sub-Saharan Africa: A Scoping Review.AIDS and behavior · 2023Article
- Pathways to Depression and Poor Quality of Life Among Adolescents in Western Kenya: Role of Anticipated HIV Stigma, HIV Risk Perception, and Sexual Behaviors.AIDS and behavior · 2021Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
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Abstract
purposeMinimal research has been conducted to understand how fatigue influences quality of life (QOL) among adolescents living with HIV. The purpose of the study was to examine the relationship between fatigue, sleep disturbance, depression, anxiety, pain and QOL among adolescents receiving antiretroviral therapy (ART).
methodsUsing a cross-sectional survey design, we studied 134 South African adolescents receiving an ART at community clinics.
resultsParticipants in general reported low levels of fatigue, insomnia, distress and pain and non-problematic levels of QOL. In the regression model, the linear combination of these variables explained 49% of the variance in QOL, a large effect size. Insomnia, anxiety, and depression significantly predicted QOL but surprisingly fatigue and pain did not.
conclusionsMany members of the sample experienced non-clinical levels of sleep disturbance, fatigue and psychosocial distress. Similarly, QOL was within the normal range. These findings are surprising as the commonly held assumption is that adolescents living with HIV, especially those of poorer socio-economic backgrounds, would experience lower QOL than the norm. Even though scores on the instruments measuring these variables fell in the non-clinical range, they were still robustly predictive of poor QOL. Future research may address the relationship between self-reported adherence and QOL, possibly by examining the role of viral load as a mediating variable. Further research may also focus on non-adherent adolescents to understand the ways in which fatigue and other factors such as school functioning and social interaction influence QOL.
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