Evidence map›Paper›PMID 30244335›Full record

ArticleWorld journal of urology2019

New study suggests patients with advanced prostate cancer on androgen deprivation therapy need more dialogue with health care provider, especially around cardiovascular risk.

Axel Merseburger, Anne Bro Falkenberg, Olga J Kornilova

Abstract read
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In one paragraph

Article in World journal of urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Axel MerseburgerUniversity Hospital Schleswig-Holstein, Ratzeburger Allee 160, 23538, Lübeck, Germany. axel.merseburger@uksh.de.
Anne Bro FalkenbergFerring Pharmaceuticals, Kay Fiskers Plads 11, Copenhagen, Denmark.
Olga J KornilovaFerring International Center, Chemin de la Vergognausaz 50, Saint-Prex, Switzerland.
Ferring Pharmaceuticals (Denmark) · DKFerring Pharmaceuticals (Switzerland) · CHUniversity of Lübeck · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo study the current level of patients' awareness, and patient-health care provider (HCP) dialogue with respect to treatment-related risks, especially cardiovascular risk (CVR) associated with advanced prostate cancer (PCa) treatment.

methodsThis 10-min online survey summarised data by treatment, region, and CVR (high or low).

resultsOf the 411 patients, 83% were at high CVR while only 8% patients were aware of CVR associated with PCa treatment, majority of which (80%) were informed about this risk by HCPs. No significant difference in treatment approach was reported, regardless of patient's CVR status. Compared to other potential risks, patients were more likely to initiate discussion about heart problems with HCPs (38% patients). When prompted, 26% patients rated heart problems as the most concerning risk factor, and this concern was twice in patients with high CVR (28%) versus low CVR (14%). Lifestyle modifications were made by 64% patients, of which 45% patients reported an improvement in overall well-being. Improved diet was the most adopted lifestyle modification.

conclusionThere is a need to enhance a constant patient-HCP dialogue, and both groups need to make a conscious effort in that direction. This would help in increasing patients' awareness of risks, having better treatment choice and acceptance, and reducing side-effects.

Indexed as

Health Knowledge, Attitudes, PracticePatient Education as TopicAgedAged, 80 and overAndrogen AntagonistsCardiovascular DiseasesCommunicationHealth PersonnelHumansMaleMiddle AgedNeoplasm StagingPhysician-Patient RelationsProstatic NeoplasmsRisk FactorsAndrogen AntagonistsCardiovascular riskHormone therapyOnline surveyPatient–physician discussionsProstate cancer

Identifiers

PMID30244335
OpenAlexW2894089271

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.