Evidence map›Paper›PMID 30244117›Full record

ArticleUrology2018

Comparison of Postradical Cystectomy Ileus Rates Using GIA-80 Versus GIA-60 Intestinal Stapler Device.

Mazyar Ghanaat, Andrew G Winer, Daniel D Sjoberg, Bing Ying Poon, Mahyar Kashan, Amy L Tin, John P Sfakianos, Eugene K Cha, Timothy F Donahue, Guido Dalbagni and 4 more

Abstract readComparative Study
In one paragraph

Article in Urology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mazyar GhanaatUrology Service at the Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY. Electronic address: ghanaatm@mskcc.org.
Andrew G WinerSUNY Downstate College of Medicine and Kings County Hospital Center, New York, NY.
Daniel D SjobergDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY.
Bing Ying PoonDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY.
Mahyar KashanUrology Service at the Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY; SUNY Downstate College of Medicine and Kings County Hospital Center, New York, NY.
Amy L TinDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY.
John P SfakianosDepartment of Urology, Icahn School of Medicine at Mount Sinai, New York, NY.
Eugene K ChaUrology Service at the Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.
Timothy F DonahueUrology Service at the Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.
Guido DalbagniUrology Service at the Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.
Harry W HerrUrology Service at the Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.
Bernard H BochnerUrology Service at the Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.
Andrew J VickersDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY.
S Machele DonatUrology Service at the Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
UROLOGY ONCOLOGY RESEARCH TRAINING GRANTT32CA082088 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Brett Stewart Carver · 1999 to 2026
$7.1M
NCI NIH HHS P30 CA008748NCI NIH HHS T32 CA082088
6 · The paper itself

Abstract

objectiveTo assess the impact on recovery of bowel function using an 80 mm versus 60 mm gastrointestinal anastomosis (GIA) stapler following radical cystectomy and urinary diversion (RC/UD) for bladder cancer.

methodsWe identified 696 patients using a prospectively maintained RC/UD database from January 2006 to November 2010. Two nonrandomized consecutive cohorts were compared. Patients between January 2006- and December 2007 (n = 180) were treated using a 60 mm GIA stapler, and 331 patients between January 2008 and December 2010 were subject to an 80 mm GIA stapler. All patients were treated on the same standardized postoperative recovery pathway. After accounting for baseline patient and perioperative characteristics, using a multivariable logistic regression model, we directly compared rates of postoperative ileus using a standardized definition.

resultsOf 511 evaluable patients, ileus was observed in 32% (57/180) for 60 mm GIA versus 33% (110/331) for the 80 mm GIA. Preoperative renal function, age, gender, body mass index, and type of diversion were comparable between cohorts. On multivariate analysis, stapler size was not significantly associated with the development of ileus (GIA-60 vs GIA-80: OR 1.11; 95% CI 0.75, 1.66; P = .6). Positive fluid balance was associated with an increased risk (P = .019) and female sex a decreased risk (P = .008) of developing ileus compared to patients with negative fluid balance.

conclusionThe size of the intestinal bowel anastomosis (GIA 80 mm vs 60 mm) does not independently impact the time to bowel recovery following RC/UD.

Indexed as

AgedAnastomosis, SurgicalCystectomyFemaleHumansIleusIntestinesMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesRisk FactorsSurgical StaplersTreatment OutcomeUrinary BladderUrinary Bladder Neoplasms

Identifiers

PMID30244117
PMCPMC6526537

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.