Observational studyEBioMedicine2018
Liver Injury in Uncomplicated Malaria is an Overlooked Phenomenon: An Observational Study.
Open access · goldAbstract readObservational Study
In one paragraph
Observational study in EBioMedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 75 citations in OpenAlex.
- Single low-dose tafenoquine combined with dihydroartemisinin-piperaquine to reduce Plasmodium falciparum transmission in Ouelessebougou, Mali: a phase 2, single-blind, randomised clinical trial.The Lancet. Microbe · 2022Trial
- Repeat controlled human malaria infection of healthy UK adults with blood-stageFrontiers in immunology · 2022Trial
- Hepatic safety and tolerability of cipargamin (KAE609), in adult patients with Plasmodium falciparum malaria: a randomized, phase II, controlled, dose-escalation trial in sub-Saharan Africa.Malaria journal · 2021Trial
- Safety and parasite clearance of artemisinin-resistant Plasmodium falciparum infection: A pilot and a randomised volunteer infection study in Australia.PLoS medicine · 2020Trial
- Inflammation and Routine Laboratory Associations in Imported Falciparum Malaria Assessed by Partial Correlation Analysis.Acta parasitologica · 2026Article
- Beyond the mouse: organoids, spheroids, and organs-on-chips as the (inevitable) future of malaria research?Malaria journal · 2026Review
- Article
- Acute Liver Failure Due to Plasmodium falciparum: A Rare Case from a Non-Endemic Country.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2026Article
- Malaria: 11-Year Experience With Imported Cases at a German University Hospital and Epidemiological Trends Amid the COVID-19 Pandemic.Journal of parasitology research · 2026Article
- Age is an intrinsic driver of inflammatory responses to malaria.Nature communications · 2025Article
- Plasmodium falciparum infection induces T cell tolerance that is associated with decreased disease severity upon re-infection.The Journal of experimental medicine · 2025Article
- Aqueous extract of Enantia chlorantha Oliv. demonstrates antimalarial activity and improves redox imbalance and biochemical alterations in mice.BMC complementary medicine and therapies · 2025Article
- Assessing the efficacy of iso-mukaadial acetate and betulinic acid against selected Plasmodium falciparum glycolytic pathway proteins: in silico and in vitro studies.BMC chemistry · 2025Article
- Article
- Elucidation of the Active Agents in a West African Ground Herbal Medicine Formulation That Elicit Antimalarial Activities in In Vitro and In Vivo Models.Molecules (Basel, Switzerland) · 2024Article
- Socioeconomic determinants of malaria and hepatitis infections: insights from the Federal Medical Center, Makurdi, North Central, Nigeria.BMC public health · 2024Article
- Antiparasitic Evaluation of Aquiluscidin, a Cathelicidin Obtained fromPathogens (Basel, Switzerland) · 2024Article
- Hepatitis B Virus Infection: A Mini Review.Viruses · 2024Review
- The effect of dosage on the protective efficacy of whole-sporozoite formulations for immunization against malaria.NPJ vaccines · 2023Article
- A systematic analysis of the human immune response to Plasmodium vivax.The Journal of clinical investigation · 2023Article
Corrections and comments
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Authors and funding
14 authors at 3 institutions in 2 countries.
Isaie J ReulingDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address: isaie.reuling@radboudumc.nl.
Gerdie M de JongHarbour Hospital, Institute for Tropical Diseases, Rotterdam, the Netherlands; Department of Medical Microbiology and Infectious Diseases, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Xi Zen YapDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, the Netherlands.
Muhammad AsgharDivision of Infectious Diseases, Department of Medicine Solna, Karolinska Institute, Stockholm, Sweden.
Jona WalkDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, the Netherlands.
Lisanne A van de SchansDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, the Netherlands.
Rob KoelewijnDepartment of Medical Microbiology and Infectious Diseases, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Anna FärnertDivision of Infectious Diseases, Department of Medicine Solna, Karolinska Institute, Stockholm, Sweden.
Quirijn de MastDepartment of Internal Medicine, Radboud university medical center, Nijmegen, the Netherlands.
Andre J van der VenDepartment of Internal Medicine, Radboud university medical center, Nijmegen, the Netherlands.
Teun BousemaDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, the Netherlands.
Jaap J van HellemondDepartment of Medical Microbiology and Infectious Diseases, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Perry J J van GenderenHarbour Hospital, Institute for Tropical Diseases, Rotterdam, the Netherlands; Department of Medical Microbiology and Infectious Diseases, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Robert W SauerweinDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address: robert.sauerwein@radboudumc.nl.
Radboud University Nijmegen · NLErasmus MC · NLKarolinska Institutet · SE
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Chemical and Drug Induced Liver InjuryAdultAntimalarialsCytokinesFemaleHumansInflammationLiver Function TestsMalaria, FalciparumMaleMiddle AgedOxidative StressAntimalarialsCytokinesInflammationLiver injuryMalariaOxidative stressPathogenesis
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.