Evidence map›Paper›PMID 30243292›Full record

ReviewJournal of nanobiotechnology2018

Recent advances in graphene-based biosensor technology with applications in life sciences.

Janire Peña-Bahamonde, Hang N Nguyen, Sofia K Fanourakis, Debora F Rodrigues

Abstract readReview
In one paragraph

Review in Journal of nanobiotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 125 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
125citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

125 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  12. Multifunctional Conductive Nanofibers for Self-Powered Glucose Biosensors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
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65 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Janire Peña-BahamondeDepartment of Civil and Environmental Engineering, University of Houston, Houston, TX, 77204-4003, USA.
Hang N NguyenDepartment of Civil and Environmental Engineering, University of Houston, Houston, TX, 77204-4003, USA.
Sofia K FanourakisDepartment of Civil and Environmental Engineering, University of Houston, Houston, TX, 77204-4003, USA.
Debora F RodriguesDepartment of Civil and Environmental Engineering, University of Houston, Houston, TX, 77204-4003, USA. dfrigirodrigues@uh.edu.ORCID http://orcid.org/0000-0002-3124-1443

Funding

National Science Foundation 1150255National Science Foundation 1705511NPRP grant 9-318-1-064USDA National Institute of Food and Agriculture 2018-67022-27969
6 · The paper itself

Abstract

Graphene's unique physical structure, as well as its chemical and electrical properties, make it ideal for use in sensor technologies. In the past years, novel sensing platforms have been proposed with pristine and modified graphene with nanoparticles and polymers. Several of these platforms were used to immobilize biomolecules, such as antibodies, DNA, and enzymes to create highly sensitive and selective biosensors. Strategies to attach these biomolecules onto the surface of graphene have been employed based on its chemical composition. These methods include covalent bonding, such as the coupling of the biomolecules via the 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride and N-hydroxysuccinimide reactions, and physisorption. In the literature, several detection methods are employed; however, the most common is electrochemical. The main reason for researchers to use this detection approach is because this method is simple, rapid and presents good sensitivity. These biosensors can be particularly useful in life sciences and medicine since in clinical practice, biosensors with high sensitivity and specificity can significantly enhance patient care, early diagnosis of diseases and pathogen detection. In this review, we will present the research conducted with antibodies, DNA molecules and, enzymes to develop biosensors that use graphene and its derivatives as scaffolds to produce effective biosensors able to detect and identify a variety of diseases, pathogens, and biomolecules linked to diseases.

Indexed as

AnimalsBiosensing TechniquesGraphiteHumansImmobilized Nucleic AcidsImmobilized ProteinsModels, MolecularNanostructuresOxidesGraphiteImmobilized Nucleic AcidsImmobilized ProteinsOxidesAntibodyDetectionDNAEnzymeGrapheneGraphene oxideNano-biosensorsPathogens

Identifiers

PMID30243292
PMCPMC6150956

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.