ArticleClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2018
Periodic limb movements in sleep: Prevalence and associated sleepiness in the Wisconsin Sleep Cohort.
Article in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Pooled it
- Association between homocysteine and periodic limb movement during sleep in samples from the São Paulo epidemiological sleep study (EPISONO): Homocysteine and PLMS in the EPISONO study.Sleep and biological rhythms · 2026Article
- Periodic limb movements during sedation and general anesthesia in elderly patients: a prospective observational study.Journal of clinical monitoring and computing · 2026Observational
- Periodic limb movements in Parkinson's disease: a critical review of pathophysiology and a framework for clinical management.NPJ Parkinson's disease · 2026Review
- Walking the fine line between OSA and aging.Sleep & breathing = Schlaf & Atmung · 2025Review
- The Validation of the SOMNOwatch™ Actigraphy System for Periodic Limb Movements in Sleep Assessment.Clocks & sleep · 2024Article
- Positional Obstructive Sleep Apnea and Periodic Limb Movements During Sleep: A Large Multicenter Study.Clinical and experimental otorhinolaryngology · 2024Article
- Proteomic insights into the pathophysiology of periodic limb movements and restless legs syndrome.Sleep health · 2024Article
- Prevalence and Course of Idiopathic Hypersomnia in the Wisconsin Sleep Cohort Study.Neurology · 2024Article
- [Identification of restless legs syndrome in polysomnography studies and its association with other variables].Revista de neurologia · 2022Article
- Prevalence of common sleep disorders in a middle-aged community sample.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
- Sex Differences in Excessive Daytime Sleepiness Among Patients With Obstructive Sleep Apnea.Journal of clinical neurology (Seoul, Korea) · 2022Article
- Association between Self-Perceived Periodic Limb Movement during Sleep and Excessive Daytime Sleepiness Depend on Restless Leg Symptoms in Korean Adolescents.International journal of environmental research and public health · 2022Article
- Clinical characteristics of periodic limb movements during sleep categorized by continuous positive airway pressure titration polysomnography in patients with obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2022Article
- Availability of Home sleep apnea test equipment LS-140 on a comparison with Polysomnography.Fujita medical journal · 2022Article
- Management of Sleep Disturbances in Parkinson's Disease.Journal of Parkinson's disease · 2022Review
- Genetic risk for subjective reports of insomnia associates only weakly with polygraphic measures of insomnia in 2,770 adults.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
- Periodic limb movements during sleep: a narrative review.Journal of thoracic disease · 2021Review
- Periodic limb movements during sleep may reduce excessive daytime sleepiness in men with obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2020Article
- Reinventing polysomnography in the age of precision medicine.Sleep medicine reviews · 2020Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesPeriodic limb movements in sleep (PLMS) are thought to be prevalent in elderly populations, but their impact on quality of life remains unclear. We examined the prevalence of PLMS, impact of age on prevalence, and association between PLMS and sleepiness.
methodsWe identified limb movements in 2335 Wisconsin Sleep Cohort polysomnograms collected over 12 years. Prevalence of periodic limb movement index (PLMI) ≥15 was calculated at baseline (n = 1084). McNemar's test assessed changes in prevalence over time. Association of sleepiness and PLMS evaluated using linear mixed modeling and generalized estimating equations. Models adjusted for confounders.
resultsPrevalence of PLMI ≥15 at baseline was 25.3%. Longitudinal prevalence increased significantly with age (p = 2.97 × 10
conclusionsA significant number of adults have PLMS and prevalence increased with age. No noteworthy association between PLMI category and sleepiness unless stratified by RLS symptoms. SIGNIFICANCE: Our results indicate that RLS and PLMS may have distinct clinical consequences and interactions that can help guide treatment approach.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.