ArticleDrug and alcohol dependence2018
Hepatitis C virus prevalence and estimated incidence among new injectors during the opioid epidemic in New York City, 2000-2017: Protective effects of non-injecting drug use.
Article in Drug and alcohol dependence, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Hepatitis C Virus Infection in Indigenous Populations in the United States and Canada.Epidemiologic reviews · 2019Pooled it
- Article
- Article
- Association of opioid use disorder with healthcare utilization and cost in a public health system.Addiction (Abingdon, England) · 2022Article
- Mobile low-threshold buprenorphine integrated with infectious disease services.Journal of substance abuse treatment · 2022Article
- Drug-related deaths in a population-level cohort of people living with and without hepatitis C virus in British Columbia, Canada.The International journal on drug policy · 2020Article
- Hepatitis C incidence and prevalence among Puerto Rican people who use drugs in New York City.Global public health · 2020Article
- Psychosocial Factors and the Care Cascade for Hepatitis C Treatment Colocated at a Syringe Service Program.The Journal of infectious diseases · 2020Article
- Hepatitis C Virus (HCV) Care Continuum Outcomes and HCV Community Viral Loads Among Patients in an Opioid Treatment Program.The Journal of infectious diseases · 2020Article
- Treating Opioid Use Disorder and Related Infectious Diseases in the Criminal Justice System.Infectious disease clinics of North America · 2020Review
- Cost-effectiveness of Universal and Targeted Hepatitis C Virus Screening in the United States.JAMA network open · 2020Article
- Chronic Methadone Use Alters the CD8Journal of immunology (Baltimore, Md. : 1950) · 2020Article
- Contemporary Epidemiology of Cirrhosis.Current treatment options in gastroenterology · 2019Review
- Association Between Time to First RNA-Negative Test Result Among People With Hepatitis C Virus Infection and Homelessness or Testing at a Correctional or Substance Use Treatment Facility, New York City.Public health reports (Washington, D.C. : 1974)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
objectiveAssess hepatitis C virus (HCV) prevalence and incidence among person who began injecting drugs during the opioid epidemic in New York City (NYC) and identify possible new directions for reducing HCV infection among persons who inject drugs.
methods846 persons who began injecting drugs between 2000 and 2017 were recruited from persons entering Mount Sinai Beth Israel substance use treatment programs. A structured interview was administered and HCV antibody testing conducted. Protective effects of non-injecting drug use were examined among persons who "reversed transitioned" to non-injecting drug use and persons who used non-injected heroin in addition to injecting.
resultsParticipants were 79% male, 41% White, 15% African-American, 40% Latinx, with a mean age of 35. Of those who began injecting in 2000 or later, 97 persons (11%) "reverse transitioned" back to non-injecting drug use. Reverse transitioning was strongly associated with lower HCV seroprevalence (30% versus 47% among those who continued injecting, p < 0.005). Among those who continued injecting, HCV seropositivity was inversely associated with current non-injecting heroin use (AOR = 0.72, 95%CI 0.52-0.99). HCV incidence among persons continuing to inject was estimated as 13/100 person-years. HCV seropositive persons currently injecting cocaine were particularly likely to report behavior likely to transmit HCV.
conclusionsSimilar to other locations in the US, NYC is experiencing high rates of HCV infection among persons who have begun injecting since 2000. New interventions that facilitate substitution of non-injecting for injecting drug use and that reduce transmission behavior among HCV seropositives may provide additional methods for reducing HCV transmission.
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Registered trials
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