Evidence map›Paper›PMID 30242169›Full record

ArticleScientific reports2018

Stationary Computed Tomography for Space and other Resource-constrained Environments.

Avilash Cramer, Jake Hecla, Dufan Wu, Xiaochun Lai, Tim Boers, Kai Yang, Tim Moulton, Steven Kenyon, Zaven Arzoumanian, Wolfgang Krull and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
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  7. Article
  8. Radiology 2040.Radiology · 2023
    Article
  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Avilash CramerMassachusetts Institute of Technology, Cambridge, 02139, USA. avilash@mit.edu.
Jake HeclaMassachusetts Institute of Technology, Cambridge, 02139, USA.
Dufan WuHarvard Medical School, Boston, 20115, USA.
Xiaochun LaiHarvard Medical School, Boston, 20115, USA.
Tim BoersUniversity of Twente, Enschede, 7522, NB, Netherlands.
Kai YangHarvard Medical School, Boston, 20115, USA.
Tim MoultonMassachusetts General Hospital, Boston, 02114, USA.
Steven KenyonNASA's Goddard Space Flight Center, Greenbelt, 02771, USA.
Zaven ArzoumanianNASA's Goddard Space Flight Center, Greenbelt, 02771, USA.
Wolfgang KrullMassachusetts General Hospital, Boston, 02114, USA.
Keith GendreauNASA's Goddard Space Flight Center, Greenbelt, 02771, USA.
Rajiv GuptaHarvard Medical School, Boston, 20115, USA.

Funding

Neuroimaging Training ProgramT32EB001680 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BRUCE R ROSEN · 2003 to 2026
$3.8M
DOD | Air Force Office of Scientific Research (AF Office of Scientific Research) FA8650-17-C-9113DOD | U.S. Army Medical Research and Materiel Command (Medical Research and Materiel Command, U.S. Army Medical Department) W81XWH-13-2-0067DOD | U.S. Army Medical Research and Materiel Command (Medical Research and Materiel Command, U.S. Army Medical Department) W81XWH-15-C-0052DOD | U.S. Army Medical Research and Materiel Command (Medical Research and Materiel Command, U.S. Army Medical Department) W81XWH-17-C-0068NIBIB NIH HHS T32 EB001680
6 · The paper itself

Abstract

Computed tomography (CT) is used to diagnose many emergent medical conditions, including stroke and traumatic brain injuries. Unfortunately, the size, weight, and expense of CT systems make them largely inaccessible for patients outside of major hospitals. We have designed a module containing multiple miniature x-ray sources that could allow for CT systems to be significantly lighter, smaller, and cheaper, and to operate without any moving parts. We have developed a novel photocathode-based x-ray source, created by depositing a thin film of magnesium on an electron multiplier. When illuminated by a UV LED, this photocathode emits a beam of electrons, with a beam current of up to 1 mA. The produced electrons are accelerated through a high voltage to a tungsten target. These sources are individually addressable and can be pulsed rapidly, through electronic control of the LEDs. Seven of these sources are housed together in a 17.5 degree arc within a custom vacuum manifold. A full ring of these modules could be used for CT imaging. By pulsing the sources in series, we are able to demonstrate x-ray tomosynthesis without any moving parts. With a clinical flat-panel detector, we demonstrate 3D acquisition and reconstructions of a cadaver swine lung.

Indexed as

AnimalsElectronsHumansPhantoms, ImagingSwineTomography, X-Ray ComputedX-Rays

Identifiers

PMID30242169
PMCPMC6155104

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.