Evidence map›Paper›PMID 30242146›Full record

ArticleTranslational psychiatry2018

Cholinergic basal forebrain neurons regulate fear extinction consolidation through p75 neurotrophin receptor signaling.

Zoran Boskovic, Michael R Milne, Lei Qian, Hamish D Clifton, Alice E McGovern, Marion T Turnbull, Stuart B Mazzone, Elizabeth J Coulson

Open access · goldAbstract read
In one paragraph

Article in Translational psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. NgfrNature communications · 2024
    Article
  2. Article
  3. Article
  4. Basal forebrain cholinergic signaling in the basolateral amygdala promotes strength and durability of fear memories.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
    Article
  5. Article
  6. Article
  7. PTSD as an Endothelial Disease: Insights From COVID-19.Frontiers in cellular neuroscience · 2021
    Review
  8. Review
  9. Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Zoran BoskovicCentre for Ageing Dementia Research, The University of Queensland, Brisbane, QLD, 4072, Australia.
Michael R MilneCentre for Ageing Dementia Research, The University of Queensland, Brisbane, QLD, 4072, Australia.
Lei QianCentre for Ageing Dementia Research, The University of Queensland, Brisbane, QLD, 4072, Australia.ORCID http://orcid.org/0000-0002-3480-4248
Hamish D CliftonCentre for Ageing Dementia Research, The University of Queensland, Brisbane, QLD, 4072, Australia.
Alice E McGovernFaculty of Medicine, School of Biomedical Sciences, The University of Queensland, Brisbane, QLD, 4072, Australia.
Marion T TurnbullCentre for Ageing Dementia Research, The University of Queensland, Brisbane, QLD, 4072, Australia.
Stuart B MazzoneFaculty of Medicine, School of Biomedical Sciences, The University of Queensland, Brisbane, QLD, 4072, Australia.
Elizabeth J CoulsonCentre for Ageing Dementia Research, The University of Queensland, Brisbane, QLD, 4072, Australia. e.coulson@uq.edu.au.ORCID http://orcid.org/0000-0003-3783-6197
The University of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cholinergic basal forebrain (cBF)-derived neurotransmission plays a crucial role in regulating neuronal function throughout the cortex, yet the mechanisms controlling cholinergic innervation to downstream targets have not been elucidated. Here we report that removing the p75 neurotrophin receptor (p75

Indexed as

AnimalsAxonsBasal ForebrainCholinergic NeuronsExtinction, PsychologicalFearFemaleMaleMemory ConsolidationMice, KnockoutNeural PathwaysPrefrontal CortexReceptors, Nerve Growth FactorNgfr protein, mouseReceptors, Nerve Growth Factor

Identifiers

PMID30242146
PMCPMC6154972
OpenAlexW2890847321

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.