Evidence map›Paper›PMID 30242134›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

ASTN2 modulates synaptic strength by trafficking and degradation of surface proteins.

Hourinaz Behesti, Taylor R Fore, Peter Wu, Zachi Horn, Mary Leppert, Court Hull, Mary E Hatten

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 66 citations in OpenAlex.

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  11. Mice lackingProceedings of the National Academy of Sciences of the United States of America · 2024
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  16. Mice lackingbioRxiv : the preprint server for biology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Hourinaz BehestiLaboratory of Developmental Neurobiology, The Rockefeller University, New York, NY 10065.
Taylor R ForeDuke Institute for Brain Sciences, Duke University, Durham, NC 27710.
Peter WuLaboratory of Developmental Neurobiology, The Rockefeller University, New York, NY 10065.
Zachi HornLaboratory of Developmental Neurobiology, The Rockefeller University, New York, NY 10065.
Mary LeppertCenter for Development and Learning, Kennedy Krieger Institute, Baltimore, MD 21205.
Court HullDuke Institute for Brain Sciences, Duke University, Durham, NC 27710.
Mary E HattenLaboratory of Developmental Neurobiology, The Rockefeller University, New York, NY 10065; hatten@rockefeller.edu.ORCID 0000-0001-9059-660X
Rockefeller University · USDuke University · USKennedy Krieger Institute · US

Funding

Neuromodulatory Control of Cerebellar Synaptic Processing and Sensory InputR01NS096289 · NINDS · DUKE UNIVERSITY · PI HULL, COURT A · 2016 to 2020
$1.7M
NINDS NIH HHS R01 NS096289Wellcome Trust
6 · The paper itself

Abstract

Surface protein dynamics dictate synaptic connectivity and function in neuronal circuits.

Indexed as

DNA Copy Number VariationsAnimalsCell MovementCells, CulturedEndocytosisGlycoproteinsHumansMiceMice, Inbred C57BLNerve Tissue ProteinsNeurodevelopmental DisordersProtein TransportProteolysisPurkinje CellsSynapsesASTN2 protein, humanGlycoproteinsNerve Tissue Proteinsautism spectrum disordercerebellumprotein degradationprotein traffickingsynapse

Identifiers

PMID30242134
PMCPMC6187130
OpenAlexW2950708207

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.