Evidence map›Paper›PMID 30242094›Full record

ArticleMolecular cancer therapeutics2018

Nano-delivery of

Nadia Saadat, Fangchao Liu, Brittany Haynes, Pratima Nangia-Makker, Xun Bao, Jing Li, Lisa A Polin, Smiti Gupta, Guangzhao Mao, Malathy P Shekhar

Open access · bronzeAbstract read
In one paragraph

Article in Molecular cancer therapeutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Ubiquitin-conjugating Enzymes in Cancer.International journal of biological sciences · 2026
    Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Nadia Saadat *Karmanos Cancer Institute, Detroit, Michigan.
Fangchao Liu *Department of Chemical Engineering and Materials Science, Wayne State University College of Engineering, Detroit, Michigan.
Brittany HaynesKarmanos Cancer Institute, Detroit, Michigan.
Pratima Nangia-MakkerKarmanos Cancer Institute, Detroit, Michigan.
Xun BaoKarmanos Cancer Institute, Detroit, Michigan.
Jing LiKarmanos Cancer Institute, Detroit, Michigan.
Lisa A PolinKarmanos Cancer Institute, Detroit, Michigan.
Smiti GuptaDepartment of Nutrition and Food Sciences, Wayne State University College of Liberal Arts and Science, Detroit, Michigan.
Guangzhao MaoDepartment of Chemical Engineering and Materials Science, Wayne State University College of Engineering, Detroit, Michigan. shekharm@karmanos.org guangzhao.mao@wayne.edu.
Malathy P ShekharKarmanos Cancer Institute, Detroit, Michigan. shekharm@karmanos.org guangzhao.mao@wayne.edu.
Wayne State University · US

Funding

Tumor Biology and Microenvironment (Program 1)P30CA022453 · NCI · WAYNE STATE UNIVERSITY · PI PAUL M STEMMER · 1985 to 2026
$68.4M
THE ROLE OF CNS INSULIN AS A MODULATOR OF DIABETIC COMPLICATIONSR25GM058905 · NIGMS · WAYNE STATE UNIVERSITY · PI CHOW, CHRISTINE S, DUNBAR, JOSEPH C · 1999 to 2020
$14.4M
TRAINING PROGRAM IN THE BIOLOGY OF CANCERT32CA009531 · NCI · WAYNE STATE UNIVERSITY · PI Larry H Matherly · 1985 to 2026
$5.3M
FUNCTIONAL PLASTICITY IN THE MAMMALIAN SPINAL CORDR01HD031550 · NICHD · WAYNE STATE UNIVERSITY · PI GOSHGARIAN, HARRY G · 1993 to 2015
$2.4M
Targeting Rad6 Postreplication DNA Repair to Treat Triple Negative Breast CancerR21CA178117 · NCI · WAYNE STATE UNIVERSITY · PI SHEKHAR, MALATHY PV · 2013 to 2015
$358k
NCI NIH HHS P30 CA022453NCI NIH HHS R21 CA178117NCI NIH HHS T32 CA009531NICHD NIH HHS R01 HD031550NIGMS NIH HHS R25 GM058905
6 · The paper itself

Abstract

The triple-negative breast cancer (TNBC) subtype, regardless of their BRCA1 status, has the poorest outcome compared with other breast cancer subtypes, and currently there are no approved targeted therapies for TNBC. We have previously demonstrated the importance of

Indexed as

DNA RepairAnimalsBRCA1 ProteinCell Line, TumorEnergy MetabolismFemaleGoldHumansMetabolic Networks and PathwaysMetal NanoparticlesMice, NudeMutationPolyethylene GlycolsThiazinesTissue DistributionTriple Negative Breast NeoplasmsBRCA1 ProteinBRCA1 protein, humanGoldPolyethylene GlycolsThiazinesUbiquitin-Conjugating Enzymes

Identifiers

PMID30242094
PMCPMC6279467
OpenAlexW2890305832

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.