Evidence map›Paper›PMID 30242073›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

Stabilization of Foxp3 by Targeting JAK2 Enhances Efficacy of CD8 Induced Regulatory T Cells in the Prevention of Graft-versus-Host Disease.

Supinya Iamsawat, Anusara Daenthanasanmak, Jessica Heinrichs Voss, Hung Nguyen, David Bastian, Chen Liu, Xue-Zhong Yu

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. FoxP3Frontiers in immunology · 2022
    Article
  9. Review
  10. Article
  11. The Binary Classification of Protein Kinases.Journal of inflammation research · 2021
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Supinya IamsawatDepartment of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425.
Anusara DaenthanasanmakDepartment of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425.
Jessica Heinrichs VossDepartment of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425.
Hung NguyenDepartment of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425.ORCID 0000-0001-9416-5137
David BastianDepartment of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425.
Chen LiuDepartment of Pathology and Laboratory Medicine, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ 08901; and.
Xue-Zhong YuDepartment of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425; yux@musc.edu.
Medical University of South Carolina · USRutgers, The State University of New Jersey · US

Funding

Effects of Foxp3-Induced Regulatory T Cells on GVHD and GVT ActivityR01CA118116 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI YU, XUE-ZHONG · 2006 to 2015
$2.2M
MicroRNA Regulates Graft-versus-Host DiseaseR01AI118305 · NIAID · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI YU, XUE-ZHONG · 2015 to 2019
$1.7M
Targeting IL-12/23 p40 Pathways for the Control of GVHDR01CA169116 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI YU, XUE-ZHONG · 2013 to 2017
$1.6M
Separation of GVH and GVL Responses Using Alloreactive CD8 iTregsR01HL137373 · NHLBI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI YU, XUE-ZHONG · 2017 to 2020
$1.5M
NCI NIH HHS R01 CA118116NCI NIH HHS R01 CA169116NHLBI NIH HHS R01 HL137373NIAID NIH HHS R01 AI118305
6 · The paper itself

Abstract

CD8

Indexed as

AnimalsCD8-Positive T-LymphocytesForkhead Transcription FactorsGraft vs Leukemia EffectJanus Kinase 2MiceT-Lymphocytes, RegulatoryForkhead Transcription FactorsFoxp3 protein, mouseJak2 protein, mouseJanus Kinase 2

Identifiers

PMID30242073
PMCPMC6200641
OpenAlexW2889974358

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.