Evidence map›Paper›PMID 30242045›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018

Theta Bursts Precede, and Spindles Follow, Cortical and Thalamic Downstates in Human NREM Sleep.

Christopher E Gonzalez, Rachel A Mak-McCully, Burke Q Rosen, Sydney S Cash, Patrick Y Chauvel, Hélène Bastuji, Marc Rey, Eric Halgren

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 78 citations in OpenAlex.

  1. The effect of zolpidem on targeted memory reactivation during sleep.Learning & memory (Cold Spring Harbor, N.Y.) · 2021
    Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Sleep Spindle Abnormalities in Preschool Children With Autism Spectrum Disability: Insights From Nap Polysomnography.Autism research : official journal of the International Society for Autism Research · 2025
    Article
  9. Article
  10. Fast ripple band high-frequency activity associated with thalamic sleep spindles in pediatric epilepsy.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2025
    Article
  11. Article
  12. Neurophysiological effects of targeting sleep spindles with closed-loop auditory stimulation.Sleep advances : a journal of the Sleep Research Society · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Cross-regional coordination of activity in the human brain during autobiographical self-referential processing.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  17. Mapping sleep's oscillatory events as a biomarker of Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Christopher E GonzalezDepartment of Neurosciences, University of California San Diego, La Jolla, California 92093, cegonzalez@ucsd.edu.
Rachel A Mak-McCullyUniversity California Berkeley, Berkeley, California 94720.
Burke Q RosenDepartment of Neurosciences, University of California San Diego, La Jolla, California 92093.ORCID 0000-0002-5049-8316
Sydney S CashDepartment of Neurology, Massachusetts General Hospital and Harvard Medical School, Harvard University, Boston, Massachusetts 02114.ORCID 0000-0002-4557-6391
Patrick Y ChauvelAix-Marseille Université, Marseille 13385, France.
Hélène BastujiCentral Integration of Pain, Lyon Neuroscience Research Center, INSERM, U1028, CNRS, UMR5292, Université Claude Bernard, Lyon, Bron, France, and.
Marc ReyAix-Marseille Université, Marseille 13385, France.
Eric HalgrenDepartments of Radiology and Neurosciences, University of California, San Diego, California 92093.
University of California San Diego · USAix-Marseille Université · FRHarvard University · USUniversité Claude Bernard Lyon 1 · FRUniversity of California, Berkeley · US

Funding

TRAINING PROGRAM IN COGNITIVE NEUROSCIENCET32MH020002 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SEJNOWSKI, TERRENCE J · 1999 to 2020
$6.1M
From ion channel dynamics to human EEG and MEG: multiscale neuronal models validated by human dataRF1MH117155 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BAZHENOV, MAKSIM V, CASH, SYDNEY S · 2018 to 2018
$3.7M
CRCNS: Integrated Empirical and Multiscale Modeling of Human Sleep SpindlesR01EB009282 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SEJNOWSKI, TERRENCE J · 2008 to 2016
$3.7M
CRCNS: Multiresolution Modeling of Human Thalamocortical Upstates and DownstatesR01MH099645 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HALGREN, ERIC · 2012 to 2016
$1.8M
NIBIB NIH HHS R01 EB009282NIMH NIH HHS R01 MH099645NIMH NIH HHS RF1 MH117155NIMH NIH HHS T32 MH020002
6 · The paper itself

Abstract

Since their discovery, slow oscillations have been observed to group spindles during non-REM sleep. Previous studies assert that the slow-oscillation downstate (DS) is preceded by slow spindles (10-12 Hz) and followed by fast spindles (12-16 Hz). Here, using both direct transcortical recordings in patients with intractable epilepsy (

Indexed as

AdultAgedCerebral CortexElectroencephalographyFemaleHumansMaleMiddle AgedSleep StagesThalamusTheta RhythmcorticothalamicdownstatesiEEGsleepspindlestheta

Identifiers

PMID30242045
PMCPMC6234298
OpenAlexW2951639334

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.