ArticleRespiratory research2018
The impact of HIV on the prevalence of asthma in Uganda: a general population survey.
Article in Respiratory research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Effect of HIV on respiratory symptoms, health status, and exertional capacity.AIDS (London, England) · 2025Pooled it
- A Descriptive Analysis of Nasal Polyposis in HIV Positive Versus HIV Negative Patients.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- HIV-associated lung disease.Nature reviews. Disease primers · 2023Review
- Circadian-Coupled Genes Expression and Regulation in HIV-Associated Chronic Obstructive Pulmonary Disease (COPD) and Lung Comorbidities.International journal of molecular sciences · 2023Review
- Health conditions in adults with HIV compared with the general population: A population-based cross-sectional analysis.EClinicalMedicine · 2022Article
- Chronic obstructive pulmonary disease prevalence and associated factors in an urban HIV clinic in a low income country.PloS one · 2021Article
- Article
- Allergy as a Disease of Dysbiosis: Is It Time to Shift the Treatment Paradigm?Frontiers in cellular and infection microbiology · 2019Review
- Influence of HIV status on the management of acute asthma exacerbations.BMJ open respiratory research · 2019Article
- Magnitude of Noncommunicable Diseases and Associated Factors among Adult People Living with HIV Attending ART Clinics of General Hospitals in Sidama Region, Ethiopia.Journal of the International Association of Providers of AIDS CareArticle
- Re-estimation of the burden of serious fungal diseases in Uganda.Therapeutic advances in infectious diseaseArticle
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Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
Abstract
backgroundHIV and asthma are highly prevalent diseases in Africa but few studies have assessed the impact of HIV on asthma prevalence in high HIV burden settings. The objective of this analysis was to compare the prevalence of asthma among persons living with HIV (PLHIV) and those without HIV participating in the Uganda National Asthma Survey (UNAS).
methodsUNAS was a population-based survey of persons aged ≥12 years. Asthma was diagnosed based on either self-reported current wheeze concurrently or within the prior 12 months; physician diagnosis; or use of asthma medication. HIV was defined based on confidential self-report. We used Poisson regression with robust standard errors to estimate asthma prevalence and the prevalence ratio (PR) for HIV and asthma.
resultsOf 3416 participants, 2067 (60.5%) knew their HIV status and 103 (5.0%) were PLHIV. Asthma prevalence was 15.5% among PLHIV and 9.1% among those without HIV, PR 1.72, (95%CI 1.07-2.75, p = 0.025). HIV modified the association of asthma with the following factors, PLHIV vs. not PLHIV: tobacco smoking (12% vs. 8%, p = < 0.001), biomass use (11% vs. 7%, p = < 0.001), allergy (17% vs. 11%, p = < 0.001), family history of asthma (17% vs. 11%, p = < 0.001), and prior TB treatment (15% vs. 10%, p = < 0.001).
conclusionIn Uganda the prevalence of asthma is higher in PLHIV than in those without HIV, and HIV interacts synergistically with other known asthma risk factors. Additional studies should explore the mechanisms underlying these associations. Clinicians should consider asthma as a possible diagnosis in PLHIV presenting with respiratory symptoms.
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