Evidence map›Paper›PMID 30241416›Full record

ArticleNanomaterials (Basel, Switzerland)2018

Gamma Irradiation-Assisted Synthesis of Cellulose Nanocrystal-Reinforced Gelatin Hydrogels.

Wan Hafizi Wan Ishak, Ishak Ahmad, Suria Ramli, Mohd Cairul Iqbal Mohd Amin

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 130 citations in OpenAlex.

  1. Article
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  3. Gelatin Adsorption onto Cellulose Nanocrystals Surfaces at Different pH: A QCM-D Study.Langmuir : the ACS journal of surfaces and colloids · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Wan Hafizi Wan IshakPolymer Research Centre (PORCE), School of Chemical Sciences and Food Technology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Bangi Selangor 43600, Malaysia. hafizi.wan29@gmail.com.
Ishak AhmadPolymer Research Centre (PORCE), School of Chemical Sciences and Food Technology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Bangi Selangor 43600, Malaysia. gading@ukm.edu.my.
Suria RamliPolymer Research Centre (PORCE), School of Chemical Sciences and Food Technology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Bangi Selangor 43600, Malaysia. su_ramli@ukm.edu.my.
Mohd Cairul Iqbal Mohd AminFaculty of Pharmacy, University Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur 50300, Malaysia. mciamin@ukm.edu.my.
National University of Malaysia · MYUniversity Kebangsaan Malaysia Medical Centre · MY

Funding

Ministry of Higher Education, Malaysia FRGS-MRSA/1/2016/STG07/UKM/01/1Universiti Kebangsaan Malaysia DIP-2016-026
6 · The paper itself

Abstract

Herein, we describe the use of gamma irradiation to prepare hydrogels comprising α-cellulose and cellulose nanocrystal (CNC)-reinforced gelatin in the absence of crosslinking agents. In this study, cellulose was extracted from rice husks by an alkali and bleaching treatment followed by acid hydrolysis to produce CNC. A semi-interpenetrating network (semi-IPN) of hydrogels was developed by the miscibility between gelatin and cellulosic materials. Compared to those prepared from α-cellulose, hydrogels prepared by dispersion of CNCs exhibited remarkably enhanced stiffness and swelling properties, which was ascribed to the uniform distribution of CNCs and their increased crystallinity. Improved pore structure, arrangement, and rigidity of CNC-reinforced gelatin hydrogels, which induced the swelling mechanism resulting in higher and faster water uptake was observed with a scanning electron microscope (SEM), compared to cellulose-reinforced gelatin hydrogels. Moreover, in vitro drug profiling demonstrated that CNC/gelatin hydrogels exhibit good drug loading/release behavior and are thus suitable for use in drug-delivery applications.

Indexed as

cellulose nanocrystalgelatinhydrogelsradiation

Identifiers

PMID30241416
PMCPMC6215172
OpenAlexW2890517411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.