Evidence map›Paper›PMID 30241410›Full record

ArticleViruses2018

Human Coronavirus Infections in Israel: Epidemiology, Clinical Symptoms and Summer Seasonality of HCoV-HKU1.

Nehemya Friedman, Hadar Alter, Musa Hindiyeh, Ella Mendelson, Yonat Shemer Avni, Michal Mandelboim

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 1 pooled it
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 1 synthesis or guideline pooled it, 111 citations in OpenAlex.

  1. Pooled it
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  15. Observational
  16. COVID-19 Alpha Variant (B.1.1.7): Humoral, memory B and T cells in COVID-19 pediatric convalescents.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2022
    Article
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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Nehemya FriedmanCentral Virology Laboratory, Ministry of Health, Chaim Sheba Medical Center, Tel-Hashomer, P.O.B. 5265601, Ramat-Gan 5290002, Israel. Nehemya.Friedman@sheba.health.gov.il.
Hadar AlterCentral Virology Laboratory, Ministry of Health, Chaim Sheba Medical Center, Tel-Hashomer, P.O.B. 5265601, Ramat-Gan 5290002, Israel. hadaralter1@gmail.com.
Musa HindiyehCentral Virology Laboratory, Ministry of Health, Chaim Sheba Medical Center, Tel-Hashomer, P.O.B. 5265601, Ramat-Gan 5290002, Israel. hindiyeh@yahoo.com.
Ella MendelsonCentral Virology Laboratory, Ministry of Health, Chaim Sheba Medical Center, Tel-Hashomer, P.O.B. 5265601, Ramat-Gan 5290002, Israel. Ella.Mendelson@sheba.health.gov.il.
Yonat Shemer AvniDepartment of Microbiology, Immunology and Genetics, and the Clinical Virology Soroka University Medical Center, Faculty of Health Sciences, Ben Gurion University of the Negev, P.O.B. 653, Beer Sheva 84105, Israel. yonat@bgu.ac.il.
Michal MandelboimCentral Virology Laboratory, Ministry of Health, Chaim Sheba Medical Center, Tel-Hashomer, P.O.B. 5265601, Ramat-Gan 5290002, Israel. michalman@sheba.health.gov.il.
Sheba Medical Center · ILTel Aviv University · ILBen-Gurion University of the Negev · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human coronaviruses (HCoVs) cause mild to severe respiratory diseases. Six types of HCoVs have been discovered, the most recent one termed the Middle East respiratory syndrome coronavirus (MERS-CoV). The aim of this study is to monitor the circulation of HCoV types in the population during 2015⁻2016 in Israel. HCoVs were detected by real-time PCR analysis in 1910 respiratory samples, collected from influenza-like illness (ILI) patients during the winter sentinel influenza survey across Israel. Moreover, 195 HCoV-positive samples from hospitalized patients were detected during one year at Soroka University Medical Center. While no MERS-CoV infections were detected, 10.36% of patients in the survey were infected with HCoV-OC43 (43.43%), HCoV-NL63 (44.95%), and HCoV-229E (11.62%) viruses. The HCoVs were shown to co-circulate with respiratory syncytial virus (RSV) and to appear prior to influenza virus infections. HCoV clinical symptoms were more severe than those of RSV infections but milder than influenza symptoms. Hospitalized patients had similar HCoV types percentages. However, while it was absent from the public winter survey, 22.6% of the patients were HCoV-HKU1 positives, mainly during the spring-summer period.

Indexed as

AdolescentAdultAgedChildChild, PreschoolChi-Square DistributionCoronavirusCoronavirus InfectionsGenome, ViralHumansInfantIsraelMiddle AgedPrevalenceRespiratory Syncytial VirusesSeasonsHCoV-229EHCoV-HKU1HCoV-NL63HCoV-OC43human coronavirusIsrael

Identifiers

PMID30241410
PMCPMC6213580
OpenAlexW2889894082

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.