Evidence map›Paper›PMID 30241312›Full record

ArticleLife (Basel, Switzerland)2018

Controlled Construction of Stable Network Structure Composed of Honeycomb-Shaped Microhydrogels.

Masayuki Hayakawa, Satoshi Umeyama, Ken H Nagai, Hiroaki Onoe, Masahiro Takinoue

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Masayuki HayakawaRIKEN Center for Biosystems Dynamics Research, Kobe, Hyogo 650-0047, Japan. masayuki.hayakawa@riken.jp.
Satoshi UmeyamaDepartment of Computer Science, School of Computing, Tokyo Institute of Technology, Yokohama, Kanagawa 226-8502, Japan. hozzyyyyyyy@gmail.com.
Ken H NagaiSchool of Materials Science, Japan Advanced Institute of Science and Technology, Nomi, Ishikawa 923-1292, Japan. k-nagai@jaist.ac.jp.ORCID 0000-0002-8286-3111
Hiroaki OnoeDepartment of Mechanical Engineering, Keio University, Yokohama, Kanagawa 223-8522, Japan. onoe@mech.keio.ac.jp.
Masahiro TakinoueDepartment of Computer Science, School of Computing, Tokyo Institute of Technology, Yokohama, Kanagawa 226-8502, Japan. takinoue@c.titech.ac.jp.ORCID 0000-0002-3874-2670
Tokyo Institute of Technology · JPJapan Advanced Institute of Science and Technology · JPKeio University · JPRIKEN Center for Biosystems Dynamics Research · JP

Funding

Japan Society for the Promotion of Science 18K19834, 17H01813
6 · The paper itself

Abstract

Recently, the construction of models for multicellular systems such as tissues has been attracting great interest. These model systems are expected to reproduce a cell communication network and provide insight into complicated functions in living systems./Such network structures have mainly been modelled using a droplet and a vesicle. However, in the droplet and vesicle network, there are difficulties attributed to structural instabilities due to external stimuli and perturbations. Thus, the fabrication of a network composed of a stable component such as hydrogel is desired. In this article, the construction of a stable network composed of honeycomb-shaped microhydrogels is described. We produced the microhydrogel network using a centrifugal microfluidic technique and a photosensitive polymer. In the network, densely packed honeycomb-shaped microhydrogels were observed. Additionally, we successfully controlled the degree of packing of microhydrogels in the network by changing the centrifugal force. We believe that our stable network will contribute to the study of cell communication in multicellular systems.

Indexed as

artificial cell/tissuecell communicationmicrofluidicsmicrohydrogel network

Identifiers

PMID30241312
PMCPMC6316562
OpenAlexW2892075571

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.