ArticleJournal of global oncology2018
Establishing a Pediatric Hematology-Oncology Program in Botswana.
Article in Journal of global oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Implementation factors of non-communicable disease policies and programmes for children and youth in low-income and middle-income countries: a systematic review.BMJ paediatrics open · 2024Pooled it
- Childhood cancer survival in low- and middle-income countries and the Global South: emerging evidence and critical gaps from a scoping review of observational studies.EJC paediatric oncology · 2025Review
- Outcomes of Wilms tumor therapy in Lilongwe, Malawi, 2016-2021: Successes and ongoing research priorities.Pediatric blood & cancer · 2023Article
- Bibliometric analysis of cancer research outputs in Botswana between 2009 and 2021.Journal of cancer policy · 2023Review
- A di-electrophoretic simulation procedure of iron-oxide micro-particle drug attachment system for leukemia treatment using COMSOL software: a potential treatment reference for LMICs.Frontiers in medical technology · 2023Article
- "I Want to be President of Liberia": Reflections on Pediatric Cancer Management in West Africa.Global pediatric health · 2022Article
- Striving to reduce suffering: A Phenomenological Study of nurses experience in caring for children with cancer in Ghana.Nursing open · 2021Article
- Pediatric Oncology Clinical Trials and Collaborative Research in Africa: Current Landscape and Future Perspectives.JCO global oncology · 2020Review
- Childhood cancers in a section of the South African private health sector: Analysis of medicines claims data.Health SA = SA Gesondheid · 2020Article
- Cancer care workforce in Africa: perspectives from a global survey.Infectious agents and cancer · 2019Article
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13 authors.
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Abstract
purposeAnnually, 300,000 children are diagnosed with cancer, and the majority of these children live in low- and middle-income countries (LMICs). Currently, there is incomplete information on pediatric cancer incidence, diagnosis distribution, and treatment outcomes in Africa. Since 2007, a pediatric hematology-oncology program has been operating in Botswana through a partnership between the Botswana government, Baylor College of Medicine, and Texas Children's Hospital.
methodsTo better understand patient characteristics and outcomes at Botswana's only pediatric cancer program, a hospital-based data base-the Botswana Pediatric Oncology Database-was established in 2014. Children younger than 18 years of age at the time of diagnosis who presented between 2008 and 2015 were included. Data for this study were extracted in February 2016.
resultsOf the 240 potential enrollees, 185 (77%) children met eligibility for this study. The median age was 6.4 years, and 50.8% were male. Leukemia was the most common malignancy representing 18.9% of the cohort and 88.1% of the total cohort had a histopathologic diagnosis. HIV seropositivity was confirmed in 13.5%. The 2-year overall survival of all pediatric cancer diagnoses was 52.4%. Abandonment of treatment occurred in 3.8% of patients.
conclusionIn the first 9 years of the program, capacity has been developed through a longstanding partnership between Botswana and Baylor College of Medicine/Texas Children's Hospital that has led to children receiving care for cancer and blood disorders. Although continued improvements are necessary, outcomes to date indicate that children with cancer in Botswana can be successfully diagnosed and treated.
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