Evidence map›Paper›PMID 30241271›Full record

Observational studyJournal of global oncology2018

Analgesic Prescription Patterns and Pain Outcomes in Southeast Asia: Findings From the Analgesic Treatment of Cancer Pain in Southeast Asia Study.

Dang Huy Quoc Thinh, Wimonrat Sriraj, Marzida Mansor, Kian Hian Tan, Cosphiadi Irawan, Johan Kurnianda, Yen Phi Nguyen, Annielyn Ong-Cornel, Yacine Hadjiat, Hanlim Moon and 1 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of global oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Updated epidemiology of gastrointestinal cancers in East Asia.Nature reviews. Gastroenterology & hepatology · 2023
    Review
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Dang Huy Quoc ThinhDang Huy Quoc Thinh, Ho Chi Minh City Oncology Hospital, Ho Chi Minh City; Yen Phi Nguyen, Vietnam National Cancer Hospital, Hanoi, Vietnam; Wimonrat Sriraj, Srinagarind Hospital, Khon Kaen, Thailand; Marzida Mansor, University of Malaya, Kuala Lumpur, Malaysia; Kian Hian Tan, Singapore General Hospital; Yacine Hadjiat and Hanlim Moon, APAC LATAM MEA, Mundipharma, Singapore; Cosphiadi Irawan, Cipto Mangunkusumo General Hospital, Universitas of Indonesia, Jakarta Pusat; Johan Kurnianda, Dr Sardjito General Hospital, Yogyakarta, Indonesia; Annielyn Ong-Cornel, Veterans' Memorial Medical Centre; and Francis O. Javier, St Luke's Medical Center, Quezon City, Philippines.
Wimonrat SrirajDang Huy Quoc Thinh, Ho Chi Minh City Oncology Hospital, Ho Chi Minh City; Yen Phi Nguyen, Vietnam National Cancer Hospital, Hanoi, Vietnam; Wimonrat Sriraj, Srinagarind Hospital, Khon Kaen, Thailand; Marzida Mansor, University of Malaya, Kuala Lumpur, Malaysia; Kian Hian Tan, Singapore General Hospital; Yacine Hadjiat and Hanlim Moon, APAC LATAM MEA, Mundipharma, Singapore; Cosphiadi Irawan, Cipto Mangunkusumo General Hospital, Universitas of Indonesia, Jakarta Pusat; Johan Kurnianda, Dr Sardjito General Hospital, Yogyakarta, Indonesia; Annielyn Ong-Cornel, Veterans' Memorial Medical Centre; and Francis O. Javier, St Luke's Medical Center, Quezon City, Philippines.
Marzida MansorDang Huy Quoc Thinh, Ho Chi Minh City Oncology Hospital, Ho Chi Minh City; Yen Phi Nguyen, Vietnam National Cancer Hospital, Hanoi, Vietnam; Wimonrat Sriraj, Srinagarind Hospital, Khon Kaen, Thailand; Marzida Mansor, University of Malaya, Kuala Lumpur, Malaysia; Kian Hian Tan, Singapore General Hospital; Yacine Hadjiat and Hanlim Moon, APAC LATAM MEA, Mundipharma, Singapore; Cosphiadi Irawan, Cipto Mangunkusumo General Hospital, Universitas of Indonesia, Jakarta Pusat; Johan Kurnianda, Dr Sardjito General Hospital, Yogyakarta, Indonesia; Annielyn Ong-Cornel, Veterans' Memorial Medical Centre; and Francis O. Javier, St Luke's Medical Center, Quezon City, Philippines.
Kian Hian TanDang Huy Quoc Thinh, Ho Chi Minh City Oncology Hospital, Ho Chi Minh City; Yen Phi Nguyen, Vietnam National Cancer Hospital, Hanoi, Vietnam; Wimonrat Sriraj, Srinagarind Hospital, Khon Kaen, Thailand; Marzida Mansor, University of Malaya, Kuala Lumpur, Malaysia; Kian Hian Tan, Singapore General Hospital; Yacine Hadjiat and Hanlim Moon, APAC LATAM MEA, Mundipharma, Singapore; Cosphiadi Irawan, Cipto Mangunkusumo General Hospital, Universitas of Indonesia, Jakarta Pusat; Johan Kurnianda, Dr Sardjito General Hospital, Yogyakarta, Indonesia; Annielyn Ong-Cornel, Veterans' Memorial Medical Centre; and Francis O. Javier, St Luke's Medical Center, Quezon City, Philippines.
Cosphiadi IrawanDang Huy Quoc Thinh, Ho Chi Minh City Oncology Hospital, Ho Chi Minh City; Yen Phi Nguyen, Vietnam National Cancer Hospital, Hanoi, Vietnam; Wimonrat Sriraj, Srinagarind Hospital, Khon Kaen, Thailand; Marzida Mansor, University of Malaya, Kuala Lumpur, Malaysia; Kian Hian Tan, Singapore General Hospital; Yacine Hadjiat and Hanlim Moon, APAC LATAM MEA, Mundipharma, Singapore; Cosphiadi Irawan, Cipto Mangunkusumo General Hospital, Universitas of Indonesia, Jakarta Pusat; Johan Kurnianda, Dr Sardjito General Hospital, Yogyakarta, Indonesia; Annielyn Ong-Cornel, Veterans' Memorial Medical Centre; and Francis O. Javier, St Luke's Medical Center, Quezon City, Philippines.
Johan KurniandaDang Huy Quoc Thinh, Ho Chi Minh City Oncology Hospital, Ho Chi Minh City; Yen Phi Nguyen, Vietnam National Cancer Hospital, Hanoi, Vietnam; Wimonrat Sriraj, Srinagarind Hospital, Khon Kaen, Thailand; Marzida Mansor, University of Malaya, Kuala Lumpur, Malaysia; Kian Hian Tan, Singapore General Hospital; Yacine Hadjiat and Hanlim Moon, APAC LATAM MEA, Mundipharma, Singapore; Cosphiadi Irawan, Cipto Mangunkusumo General Hospital, Universitas of Indonesia, Jakarta Pusat; Johan Kurnianda, Dr Sardjito General Hospital, Yogyakarta, Indonesia; Annielyn Ong-Cornel, Veterans' Memorial Medical Centre; and Francis O. Javier, St Luke's Medical Center, Quezon City, Philippines.
Yen Phi NguyenDang Huy Quoc Thinh, Ho Chi Minh City Oncology Hospital, Ho Chi Minh City; Yen Phi Nguyen, Vietnam National Cancer Hospital, Hanoi, Vietnam; Wimonrat Sriraj, Srinagarind Hospital, Khon Kaen, Thailand; Marzida Mansor, University of Malaya, Kuala Lumpur, Malaysia; Kian Hian Tan, Singapore General Hospital; Yacine Hadjiat and Hanlim Moon, APAC LATAM MEA, Mundipharma, Singapore; Cosphiadi Irawan, Cipto Mangunkusumo General Hospital, Universitas of Indonesia, Jakarta Pusat; Johan Kurnianda, Dr Sardjito General Hospital, Yogyakarta, Indonesia; Annielyn Ong-Cornel, Veterans' Memorial Medical Centre; and Francis O. Javier, St Luke's Medical Center, Quezon City, Philippines.
Annielyn Ong-CornelDang Huy Quoc Thinh, Ho Chi Minh City Oncology Hospital, Ho Chi Minh City; Yen Phi Nguyen, Vietnam National Cancer Hospital, Hanoi, Vietnam; Wimonrat Sriraj, Srinagarind Hospital, Khon Kaen, Thailand; Marzida Mansor, University of Malaya, Kuala Lumpur, Malaysia; Kian Hian Tan, Singapore General Hospital; Yacine Hadjiat and Hanlim Moon, APAC LATAM MEA, Mundipharma, Singapore; Cosphiadi Irawan, Cipto Mangunkusumo General Hospital, Universitas of Indonesia, Jakarta Pusat; Johan Kurnianda, Dr Sardjito General Hospital, Yogyakarta, Indonesia; Annielyn Ong-Cornel, Veterans' Memorial Medical Centre; and Francis O. Javier, St Luke's Medical Center, Quezon City, Philippines.
Yacine HadjiatDang Huy Quoc Thinh, Ho Chi Minh City Oncology Hospital, Ho Chi Minh City; Yen Phi Nguyen, Vietnam National Cancer Hospital, Hanoi, Vietnam; Wimonrat Sriraj, Srinagarind Hospital, Khon Kaen, Thailand; Marzida Mansor, University of Malaya, Kuala Lumpur, Malaysia; Kian Hian Tan, Singapore General Hospital; Yacine Hadjiat and Hanlim Moon, APAC LATAM MEA, Mundipharma, Singapore; Cosphiadi Irawan, Cipto Mangunkusumo General Hospital, Universitas of Indonesia, Jakarta Pusat; Johan Kurnianda, Dr Sardjito General Hospital, Yogyakarta, Indonesia; Annielyn Ong-Cornel, Veterans' Memorial Medical Centre; and Francis O. Javier, St Luke's Medical Center, Quezon City, Philippines.
Hanlim MoonDang Huy Quoc Thinh, Ho Chi Minh City Oncology Hospital, Ho Chi Minh City; Yen Phi Nguyen, Vietnam National Cancer Hospital, Hanoi, Vietnam; Wimonrat Sriraj, Srinagarind Hospital, Khon Kaen, Thailand; Marzida Mansor, University of Malaya, Kuala Lumpur, Malaysia; Kian Hian Tan, Singapore General Hospital; Yacine Hadjiat and Hanlim Moon, APAC LATAM MEA, Mundipharma, Singapore; Cosphiadi Irawan, Cipto Mangunkusumo General Hospital, Universitas of Indonesia, Jakarta Pusat; Johan Kurnianda, Dr Sardjito General Hospital, Yogyakarta, Indonesia; Annielyn Ong-Cornel, Veterans' Memorial Medical Centre; and Francis O. Javier, St Luke's Medical Center, Quezon City, Philippines.
Francis O JavierDang Huy Quoc Thinh, Ho Chi Minh City Oncology Hospital, Ho Chi Minh City; Yen Phi Nguyen, Vietnam National Cancer Hospital, Hanoi, Vietnam; Wimonrat Sriraj, Srinagarind Hospital, Khon Kaen, Thailand; Marzida Mansor, University of Malaya, Kuala Lumpur, Malaysia; Kian Hian Tan, Singapore General Hospital; Yacine Hadjiat and Hanlim Moon, APAC LATAM MEA, Mundipharma, Singapore; Cosphiadi Irawan, Cipto Mangunkusumo General Hospital, Universitas of Indonesia, Jakarta Pusat; Johan Kurnianda, Dr Sardjito General Hospital, Yogyakarta, Indonesia; Annielyn Ong-Cornel, Veterans' Memorial Medical Centre; and Francis O. Javier, St Luke's Medical Center, Quezon City, Philippines.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo identify patterns of analgesic prescription and to explore patient-reported pain intensity, sleep disturbance, and quality of life among cancer patients with pain in Southeast Asia (SEA).

methodsThis cross-sectional observational study included 465 adult outpatients prescribed analgesics for cancer pain for 1 month or longer at 22 sites in Indonesia, Malaysia, Philippines, Singapore, Thailand, and Vietnam. Data on analgesic prescription and cancer characteristics were extracted from medical records. Pain intensity, sleep disturbance, and quality of life measures were recorded via questionnaires.

resultsMost patients (84.4%) had stage III or IV cancer. A total of 419 patients (90.7%) were prescribed opioids; of these, 42.2% received only weak opioids, whereas 57.8% received at least one strong opioid. The mean worst pain intensity during the past 24 hours was 4.76 (standard deviation [SD], 2.47) on a scale of 0 (no pain) to 10 (worst possible pain); the mean current pain intensity was 4.10 (SD, 2.61). More than half of patients (54.8%) reported sleep disturbance caused by pain in the past 7 days. The majority of patients reported problems with pain/discomfort (82.3%), usual activities (65.8%), mobility (58.2%), and anxiety/depression (56.3%). The median daily dose prescribed in oral morphine equivalents was 30 mg for both morphine and tramadol.

conclusionDespite unrelieved pain, sleep disturbance, and issues with quality of life, a notable proportion of patients were prescribed only weak opioids, and opioid doses prescribed were generally low. Efforts focused on encouragement of prescriptions with analgesic strength and/or doses proportional to the pain management needs of patients are vital to improve the status of cancer pain management in the region.

Indexed as

AdolescentAdultAgedAged, 80 and overAnalgesicsAsia, SoutheasternCancer PainFemaleHumansMaleMiddle AgedNeoplasmsNeoplasm StagingPractice Patterns, Physicians'Treatment OutcomeYoung AdultAnalgesics

Identifiers

PMID30241271
PMCPMC6223410

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.