Evidence map›Paper›PMID 30241222›Full record

ArticleJournal of global oncology2018

Characteristics of Esophageal Cancer Cases in Tanzania.

Elia J Mmbaga, Katrina V Deardorff, Beatrice Mushi, William Mgisha, Megan Merritt, Robert A Hiatt, Julius Mwaiselage, Li Zhang, Katherine Van Loon

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of global oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. A Genomic Analysis of Esophageal Squamous Cell Carcinoma in Eastern Africa.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Developing Research Education Groups in African Cancer Centers: The Experience in Tanzania.Journal of cancer education : the official journal of the American Association for Cancer Education · 2021
    Article
  13. The relationship between gastrointestinal cancers and the microbiota.The lancet. Gastroenterology & hepatology · 2021
    Review
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Elia J MmbagaElia J. Mmbaga, Beatrice Mushi, and William Mgisha, Muhimbili University of Health and Allied Sciences; Julius Mwaiselage, Ocean Road Cancer Institute, Dar es Salaam, Tanzania; Katrina V. Deardorff, Megan Merritt, Robert A. Hiatt, Li Zhang, and Katherine Van Loon, University of California, San Francisco, San Francisco, CA.
Katrina V DeardorffElia J. Mmbaga, Beatrice Mushi, and William Mgisha, Muhimbili University of Health and Allied Sciences; Julius Mwaiselage, Ocean Road Cancer Institute, Dar es Salaam, Tanzania; Katrina V. Deardorff, Megan Merritt, Robert A. Hiatt, Li Zhang, and Katherine Van Loon, University of California, San Francisco, San Francisco, CA.
Beatrice MushiElia J. Mmbaga, Beatrice Mushi, and William Mgisha, Muhimbili University of Health and Allied Sciences; Julius Mwaiselage, Ocean Road Cancer Institute, Dar es Salaam, Tanzania; Katrina V. Deardorff, Megan Merritt, Robert A. Hiatt, Li Zhang, and Katherine Van Loon, University of California, San Francisco, San Francisco, CA.
William MgishaElia J. Mmbaga, Beatrice Mushi, and William Mgisha, Muhimbili University of Health and Allied Sciences; Julius Mwaiselage, Ocean Road Cancer Institute, Dar es Salaam, Tanzania; Katrina V. Deardorff, Megan Merritt, Robert A. Hiatt, Li Zhang, and Katherine Van Loon, University of California, San Francisco, San Francisco, CA.
Megan MerrittElia J. Mmbaga, Beatrice Mushi, and William Mgisha, Muhimbili University of Health and Allied Sciences; Julius Mwaiselage, Ocean Road Cancer Institute, Dar es Salaam, Tanzania; Katrina V. Deardorff, Megan Merritt, Robert A. Hiatt, Li Zhang, and Katherine Van Loon, University of California, San Francisco, San Francisco, CA.
Robert A HiattElia J. Mmbaga, Beatrice Mushi, and William Mgisha, Muhimbili University of Health and Allied Sciences; Julius Mwaiselage, Ocean Road Cancer Institute, Dar es Salaam, Tanzania; Katrina V. Deardorff, Megan Merritt, Robert A. Hiatt, Li Zhang, and Katherine Van Loon, University of California, San Francisco, San Francisco, CA.
Julius MwaiselageElia J. Mmbaga, Beatrice Mushi, and William Mgisha, Muhimbili University of Health and Allied Sciences; Julius Mwaiselage, Ocean Road Cancer Institute, Dar es Salaam, Tanzania; Katrina V. Deardorff, Megan Merritt, Robert A. Hiatt, Li Zhang, and Katherine Van Loon, University of California, San Francisco, San Francisco, CA.
Li ZhangElia J. Mmbaga, Beatrice Mushi, and William Mgisha, Muhimbili University of Health and Allied Sciences; Julius Mwaiselage, Ocean Road Cancer Institute, Dar es Salaam, Tanzania; Katrina V. Deardorff, Megan Merritt, Robert A. Hiatt, Li Zhang, and Katherine Van Loon, University of California, San Francisco, San Francisco, CA.
Katherine Van LoonElia J. Mmbaga, Beatrice Mushi, and William Mgisha, Muhimbili University of Health and Allied Sciences; Julius Mwaiselage, Ocean Road Cancer Institute, Dar es Salaam, Tanzania; Katrina V. Deardorff, Megan Merritt, Robert A. Hiatt, Li Zhang, and Katherine Van Loon, University of California, San Francisco, San Francisco, CA.
Muhimbili University of Health and Allied Sciences · TZ

Funding

NCI NIH HHS HHSN261200800001E
6 · The paper itself

Abstract

purposeAge-standardized incidence rates for esophageal cancer (EC) in East Africa have been reported as disproportionately high compared with the worldwide incidence of nine per 100,000 population. This study aimed to characterize EC cases seen at Muhimbili National Hospital and Ocean Road Cancer Institute in Dar es Salaam, Tanzania.

methodsDemographic, clinical, and treatment variables were abstracted from charts of patients who received care for a diagnosis of EC at one or both institutions between 2011 and 2013. Categorical data were summarized as frequency counts and percentages. Continuous data were presented as medians and ranges. To compare men and women, Pearson's χ

resultsSeven hundred thirty-eight unique cases of EC were identified, of whom 68% were men and the median age was 60 years (range, 19 to 95 years). Notably, 93 cases (13%) were ≤ 40 years old at diagnosis. Squamous cell carcinoma was the dominant histology, comprising 90% of cases with documented histopathology. However, 34% of cases with a diagnosis of EC were not pathologically confirmed. The stage was documented as locoregional in 4% of cases, locally advanced in 20% of cases, metastatic in 14% of cases, and unknown in 63% of cases. Of 430 patients who received treatment at Ocean Road Cancer Institute, 76% were treated with radiation, 44% were treated with chemotherapy, 3% underwent a cancer-related surgical procedure, and 10% of cases received no cancer-directed therapy. The median overall survival for all patients was 6.9 months (95% CI, 5.0 to 12.8), regardless of stage at presentation.

conclusionBetween 2011 and 2013, cases of EC represented a large clinical burden at both institutions.

Indexed as

Carcinoma, Squamous CellEsophageal NeoplasmsAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesSurvival AnalysisTanzaniaYoung Adult

Identifiers

PMID30241222
PMCPMC6180793
OpenAlexW2610117628

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.