ReviewJournal of global oncology2018
Breast Cancer and HIV in Sub-Saharan Africa: A Complex Relationship.
Open access · goldAbstract readReview
In one paragraph
Review in Journal of global oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 37 citations in OpenAlex.
- HIV status alters immune cell infiltration and activation profile in women with breast cancer.Nature communications · 2025Article
- Real-world breast cancer treatment patterns and guideline-concordant treatment completion among Malawian women.BMC women's health · 2025Article
- Real-world breast cancer treatment patterns and guideline-concordant treatment completion among Malawian women.BMC women's health · 2025Article
- Three-year survival of breast cancer patients attending a one-stop breast care clinic nested within a primary care health facility in sub-Saharan Africa-Zambia.International journal of cancer · 2024Article
- Multiple carcinomas in a woman with HIV infection: a case report and literature review.The Journal of international medical research · 2024Review
- Navigating the Nexus: HIV and Breast Cancer-A Critical Review.International journal of molecular sciences · 2024Review
- From Incidence to Intervention: A Comprehensive Look at Breast Cancer in South Africa.Oncology and therapy · 2024Article
- An audit of breast cancer in patients 40 years and younger in two Johannesburg academic hospitals.SA journal of radiology · 2024Article
- Breast cancer in women by HIV status: A report from the South African National Cancer Registry.PloS one · 2024Article
- Preoperative Biomarkers and Survival in Chinese Breast Cancer Patients with HIV: A Propensity-Score-Matched-Cohort Study.Viruses · 2023Article
- Survival Disparities Between Patients with Breast Cancer With and Without HIV: A Research Framework.JCO global oncology · 2023Article
- Epidemiology of Breast Cancer Presentation in Botswana, South Africa, and the United States.The Journal of surgical research · 2022Article
- Impact of HIV infection on survival among women with stage I-III breast cancer: Results from the South African breast cancer and HIV outcomes study.International journal of cancer · 2022Article
- Gene therapy access: Global challenges, opportunities, and views from Brazil, South Africa, and India.Molecular therapy : the journal of the American Society of Gene Therapy · 2022Review
- Relative Dose Intensity and Pathologic Response Rates in Patients With Breast Cancer and With and Without HIV Who Received Neoadjuvant Chemotherapy.JCO global oncology · 2022Article
- Breast self-examination and its associated factors among women who attended anti-retroviral therapy clinic in Bahir Dar city administration, North West Ethiopia.SAGE open medicine · 2022Article
- Long non-coding RNA NORAD inhibition upregulates microRNA-323a-3p to suppress tumorigenesis and development of breast cancer through the PUM1/eIF2 axis.Cell cycle (Georgetown, Tex.) · 2021Article
- Prevalence and Mortality of Triple-Negative Breast Cancer in West Africa: Biologic and Sociocultural Factors.JCO global oncology · 2021Article
- Exosomal microRNA-503-3p derived from macrophages represses glycolysis and promotes mitochondrial oxidative phosphorylation in breast cancer cells by elevating DACT2.Cell death discovery · 2021Article
- Outcomes and prognostic factors for women with breast cancer in Malawi.Cancer causes & control : CCC · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 7 institutions in 3 countries.
Surbhi GroverSurbhi Grover, Yehoda M. Martei, Priya Puri, and Nicola M. Zetola, University of Pennsylvania, Philadelphia, PA; Surbhi Grover, Mohan Narasimhamurthy, and Nicola M. Zetola, University of Botswana, Gaborone, Botswana; Pooja Prabhakar, University of Texas Southwestern Medical Center, Dallas, TX; Miriam Mutebi, Aga Khan University Hospital, Nairobi, Kenya; Onyinye D. Balogun, Weill Cornell Medicine, New York, NY; Aryeh J. Price, California Institute of Technology, Pasadena; Alexandra H. Freeman, Kaiser Permanente San Francisco, San Francisco, CA; Danielle Rodin, University of Toronto, Toronto, Canada; and Sarah Rayne, Helen Joseph Hospital and University of the Witwatersrand, Johannesburg, South Africa.
Yehoda M MarteiSurbhi Grover, Yehoda M. Martei, Priya Puri, and Nicola M. Zetola, University of Pennsylvania, Philadelphia, PA; Surbhi Grover, Mohan Narasimhamurthy, and Nicola M. Zetola, University of Botswana, Gaborone, Botswana; Pooja Prabhakar, University of Texas Southwestern Medical Center, Dallas, TX; Miriam Mutebi, Aga Khan University Hospital, Nairobi, Kenya; Onyinye D. Balogun, Weill Cornell Medicine, New York, NY; Aryeh J. Price, California Institute of Technology, Pasadena; Alexandra H. Freeman, Kaiser Permanente San Francisco, San Francisco, CA; Danielle Rodin, University of Toronto, Toronto, Canada; and Sarah Rayne, Helen Joseph Hospital and University of the Witwatersrand, Johannesburg, South Africa.
Priya PuriSurbhi Grover, Yehoda M. Martei, Priya Puri, and Nicola M. Zetola, University of Pennsylvania, Philadelphia, PA; Surbhi Grover, Mohan Narasimhamurthy, and Nicola M. Zetola, University of Botswana, Gaborone, Botswana; Pooja Prabhakar, University of Texas Southwestern Medical Center, Dallas, TX; Miriam Mutebi, Aga Khan University Hospital, Nairobi, Kenya; Onyinye D. Balogun, Weill Cornell Medicine, New York, NY; Aryeh J. Price, California Institute of Technology, Pasadena; Alexandra H. Freeman, Kaiser Permanente San Francisco, San Francisco, CA; Danielle Rodin, University of Toronto, Toronto, Canada; and Sarah Rayne, Helen Joseph Hospital and University of the Witwatersrand, Johannesburg, South Africa.
Pooja PrabhakarSurbhi Grover, Yehoda M. Martei, Priya Puri, and Nicola M. Zetola, University of Pennsylvania, Philadelphia, PA; Surbhi Grover, Mohan Narasimhamurthy, and Nicola M. Zetola, University of Botswana, Gaborone, Botswana; Pooja Prabhakar, University of Texas Southwestern Medical Center, Dallas, TX; Miriam Mutebi, Aga Khan University Hospital, Nairobi, Kenya; Onyinye D. Balogun, Weill Cornell Medicine, New York, NY; Aryeh J. Price, California Institute of Technology, Pasadena; Alexandra H. Freeman, Kaiser Permanente San Francisco, San Francisco, CA; Danielle Rodin, University of Toronto, Toronto, Canada; and Sarah Rayne, Helen Joseph Hospital and University of the Witwatersrand, Johannesburg, South Africa.
Miriam MutebiSurbhi Grover, Yehoda M. Martei, Priya Puri, and Nicola M. Zetola, University of Pennsylvania, Philadelphia, PA; Surbhi Grover, Mohan Narasimhamurthy, and Nicola M. Zetola, University of Botswana, Gaborone, Botswana; Pooja Prabhakar, University of Texas Southwestern Medical Center, Dallas, TX; Miriam Mutebi, Aga Khan University Hospital, Nairobi, Kenya; Onyinye D. Balogun, Weill Cornell Medicine, New York, NY; Aryeh J. Price, California Institute of Technology, Pasadena; Alexandra H. Freeman, Kaiser Permanente San Francisco, San Francisco, CA; Danielle Rodin, University of Toronto, Toronto, Canada; and Sarah Rayne, Helen Joseph Hospital and University of the Witwatersrand, Johannesburg, South Africa.
Onyinye D BalogunSurbhi Grover, Yehoda M. Martei, Priya Puri, and Nicola M. Zetola, University of Pennsylvania, Philadelphia, PA; Surbhi Grover, Mohan Narasimhamurthy, and Nicola M. Zetola, University of Botswana, Gaborone, Botswana; Pooja Prabhakar, University of Texas Southwestern Medical Center, Dallas, TX; Miriam Mutebi, Aga Khan University Hospital, Nairobi, Kenya; Onyinye D. Balogun, Weill Cornell Medicine, New York, NY; Aryeh J. Price, California Institute of Technology, Pasadena; Alexandra H. Freeman, Kaiser Permanente San Francisco, San Francisco, CA; Danielle Rodin, University of Toronto, Toronto, Canada; and Sarah Rayne, Helen Joseph Hospital and University of the Witwatersrand, Johannesburg, South Africa.
Aryeh J PriceSurbhi Grover, Yehoda M. Martei, Priya Puri, and Nicola M. Zetola, University of Pennsylvania, Philadelphia, PA; Surbhi Grover, Mohan Narasimhamurthy, and Nicola M. Zetola, University of Botswana, Gaborone, Botswana; Pooja Prabhakar, University of Texas Southwestern Medical Center, Dallas, TX; Miriam Mutebi, Aga Khan University Hospital, Nairobi, Kenya; Onyinye D. Balogun, Weill Cornell Medicine, New York, NY; Aryeh J. Price, California Institute of Technology, Pasadena; Alexandra H. Freeman, Kaiser Permanente San Francisco, San Francisco, CA; Danielle Rodin, University of Toronto, Toronto, Canada; and Sarah Rayne, Helen Joseph Hospital and University of the Witwatersrand, Johannesburg, South Africa.
Alexandra H FreemanSurbhi Grover, Yehoda M. Martei, Priya Puri, and Nicola M. Zetola, University of Pennsylvania, Philadelphia, PA; Surbhi Grover, Mohan Narasimhamurthy, and Nicola M. Zetola, University of Botswana, Gaborone, Botswana; Pooja Prabhakar, University of Texas Southwestern Medical Center, Dallas, TX; Miriam Mutebi, Aga Khan University Hospital, Nairobi, Kenya; Onyinye D. Balogun, Weill Cornell Medicine, New York, NY; Aryeh J. Price, California Institute of Technology, Pasadena; Alexandra H. Freeman, Kaiser Permanente San Francisco, San Francisco, CA; Danielle Rodin, University of Toronto, Toronto, Canada; and Sarah Rayne, Helen Joseph Hospital and University of the Witwatersrand, Johannesburg, South Africa.
Mohan NarasimhamurthySurbhi Grover, Yehoda M. Martei, Priya Puri, and Nicola M. Zetola, University of Pennsylvania, Philadelphia, PA; Surbhi Grover, Mohan Narasimhamurthy, and Nicola M. Zetola, University of Botswana, Gaborone, Botswana; Pooja Prabhakar, University of Texas Southwestern Medical Center, Dallas, TX; Miriam Mutebi, Aga Khan University Hospital, Nairobi, Kenya; Onyinye D. Balogun, Weill Cornell Medicine, New York, NY; Aryeh J. Price, California Institute of Technology, Pasadena; Alexandra H. Freeman, Kaiser Permanente San Francisco, San Francisco, CA; Danielle Rodin, University of Toronto, Toronto, Canada; and Sarah Rayne, Helen Joseph Hospital and University of the Witwatersrand, Johannesburg, South Africa.
Danielle RodinSurbhi Grover, Yehoda M. Martei, Priya Puri, and Nicola M. Zetola, University of Pennsylvania, Philadelphia, PA; Surbhi Grover, Mohan Narasimhamurthy, and Nicola M. Zetola, University of Botswana, Gaborone, Botswana; Pooja Prabhakar, University of Texas Southwestern Medical Center, Dallas, TX; Miriam Mutebi, Aga Khan University Hospital, Nairobi, Kenya; Onyinye D. Balogun, Weill Cornell Medicine, New York, NY; Aryeh J. Price, California Institute of Technology, Pasadena; Alexandra H. Freeman, Kaiser Permanente San Francisco, San Francisco, CA; Danielle Rodin, University of Toronto, Toronto, Canada; and Sarah Rayne, Helen Joseph Hospital and University of the Witwatersrand, Johannesburg, South Africa.
Sarah RayneSurbhi Grover, Yehoda M. Martei, Priya Puri, and Nicola M. Zetola, University of Pennsylvania, Philadelphia, PA; Surbhi Grover, Mohan Narasimhamurthy, and Nicola M. Zetola, University of Botswana, Gaborone, Botswana; Pooja Prabhakar, University of Texas Southwestern Medical Center, Dallas, TX; Miriam Mutebi, Aga Khan University Hospital, Nairobi, Kenya; Onyinye D. Balogun, Weill Cornell Medicine, New York, NY; Aryeh J. Price, California Institute of Technology, Pasadena; Alexandra H. Freeman, Kaiser Permanente San Francisco, San Francisco, CA; Danielle Rodin, University of Toronto, Toronto, Canada; and Sarah Rayne, Helen Joseph Hospital and University of the Witwatersrand, Johannesburg, South Africa.
Nicola M ZetolaSurbhi Grover, Yehoda M. Martei, Priya Puri, and Nicola M. Zetola, University of Pennsylvania, Philadelphia, PA; Surbhi Grover, Mohan Narasimhamurthy, and Nicola M. Zetola, University of Botswana, Gaborone, Botswana; Pooja Prabhakar, University of Texas Southwestern Medical Center, Dallas, TX; Miriam Mutebi, Aga Khan University Hospital, Nairobi, Kenya; Onyinye D. Balogun, Weill Cornell Medicine, New York, NY; Aryeh J. Price, California Institute of Technology, Pasadena; Alexandra H. Freeman, Kaiser Permanente San Francisco, San Francisco, CA; Danielle Rodin, University of Toronto, Toronto, Canada; and Sarah Rayne, Helen Joseph Hospital and University of the Witwatersrand, Johannesburg, South Africa.
Kaiser Permanente San Francisco Medical Center · USAga Khan University Nairobi · KEThe University of Texas Southwestern Medical Center · USUniversity of Toronto · CACalifornia Institute of Technology · USSouthwestern Medical CenterUniversity of Pennsylvania · US
Funding
Shared Resources CoreU54CA190158 · NCI · UNIVERSITY OF PENNSYLVANIA · PI ROBERTSON, ERLE S. · 2014 to 2023
$4.2MNCI NIH HHS U54 CA190158
Abstract
introductionThe number and lifespan of individuals living with HIV have increased significantly with the scale-up of antiretroviral therapy. Furthermore, the incidence of breast cancer in women with HIV is growing, especially in sub-Saharan Africa (SSA). However, the association between HIV infection and breast cancer is not well understood.
methodsA literature search was performed to identify articles published in journals pertaining to breast cancer and HIV, with an emphasis on SSA. Selected US-based studies were also identified for comparison.
resultsAmong the 56 studies reviewed, the largest study examined 314 patients with breast cancer and HIV in the United States. There is no consensus on whether HIV infection acts as a pro-oncogenic or antioncogenic factor in breast cancer, and it may have no relation to breast cancer. A higher incidence of breast cancer is reported in high-income countries than in SSA, although breast cancer in SSA presents at a younger age and at a more advanced stage. Some studies show that patients with breast cancer and HIV experience worse chemotherapy toxicity than do patients without HIV. Data on treatment outcomes are limited. The largest study showed worse treatment outcomes in patients with HIV, compared with their counterparts without HIV.
conclusionHIV infection has not been associated with different clinical presentation of breast cancer. However, some evidence suggests that concurrent diagnosis of HIV with breast cancer is associated with increased therapy-related toxicity and worse outcomes. Systematic prospective studies are needed to establish whether there is a specific association between breast cancer and HIV.
Indexed as
Africa South of the SaharaAntiretroviral Therapy, Highly ActiveBreast NeoplasmsCombined Modality TherapyFemaleHIV InfectionsHumansIncidencePublic Health SurveillanceTreatment Outcome
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