ArticleBrain and behavior2018
Functional outcome and survival following spontaneous intracerebral hemorrhage: A retrospective population-based study.
Article in Brain and behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 70 citations in OpenAlex.
- Incidence and Long-Term Survival of Spontaneous Intracerebral Hemorrhage Over Time: A Systematic Review and Meta-Analysis.Frontiers in neurology · 2022Pooled it
- Cognitive Impairment After Intracerebral Hemorrhage: A Systematic Review of Current Evidence and Knowledge Gaps.Frontiers in neurology · 2021Pooled it
- Functional disability after clinically significant extracranial bleeding: a secondary analysis of the Aspirin in Reducing Events in the Elderly (ASPREE) Trial.Journal of thrombosis and haemostasis : JTH · 2025Trial
- Trajectory-Based Modeling Improves Long-Term Outcome Prediction Beyond 90-Day Assessment in ICU-Treated Intracerebral Hemorrhage.Revista de neurologia · 2026Article
- Circadian disruption of brain temperature and heart rate in two periods after intracerebral hemorrhage surgery: a retrospective study.Scientific reports · 2026Article
- Article
- Sex Differences in Young Adult Stroke Severity Using Linked Colorado-All Payer's Claims Database and the Get With The Guidelines-Stroke Registry.Journal of the American Heart Association · 2026Article
- Fibrosis-4 index and prognosis and hematoma volume: association with lobar and non-lobar intracerebral hemorrhage.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Systolic Blood Pressure Reduction with Stability as a New Therapeutic Goal in Patients with Intracerebral Hemorrhage: Results of the Pooled Analysis of ATACH 2 and INTERACT 2 Trials.Neurocritical care · 2026Article
- Lower high-density lipoprotein cholesterol level is associated with hematoma expansion in acute intracerebral hemorrhage: association with hypertensive microangiopathy.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- A Decision-Analytic Model to Evaluate Cost-Effectiveness of Regional Implementation of a Mobile Stroke Unit.Neurology · 2025Article
- International Care Bundle Evaluation in Cerebral Hemorrhage Research (I-CATCHER): Study protocol for a multicenter, batched, parallel, cluster-randomized trial with a baseline period.International journal of stroke : official journal of the International Stroke Society · 2025Article
- A novel nomogram for predicting prolonged disorders of consciousness in severe supratentorial hypertensive intracerebral hemorrhage patients.Scientific reports · 2025Article
- Impact of Dataset Size on 3D CNN Performance in Intracranial Hemorrhage Classification.Diagnostics (Basel, Switzerland) · 2025Article
- The impact of functional training based on clinical nursing pathways informed by evidence-based theory on functional recovery in patients with cerebral hemorrhage.Frontiers in neurology · 2025Article
- Functional outcome after surgical treatment for spontaneous intracerebral hemorrhages: Development of the HeMAtOma score.Brain & spine · 2025Article
- A nomogram based on systemic inflammation response index and clinical risk factors for prediction of short-term prognosis of very elderly patients with hypertensive intracerebral hemorrhage.Frontiers in medicine · 2025Article
- Spot sign score is associated with hematoma expansion and longer hospital stay but not functional outcomes in primary intracerebral hemorrhage survivors.Japanese journal of radiology · 2024Article
- Intracerebral Hemorrhage Prognosis Classification via Joint-Attention Cross-Modal Network.Brain sciences · 2024Article
- Clinical Trial Protocol for BEACH: A Phase 2a Study of MW189 in Patients with Acute Nontraumatic Intracerebral Hemorrhage.Neurocritical care · 2024Article
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAccurate and reliable clinical and radiological predictors of intracerebral hemorrhage (ICH) outcomes are needed to optimize treatment of ICH. The aim of this study was to investigate functional outcome and identify predictors of severe disability or death following ICH. MATERIALS AND
methodsRetrospective population-based study of spontaneous ICH. Clinical and radiological data were obtained from electronic medical records, and functional outcome estimated using the modified Rankin Scale (mRS) before ICH and at 3 and 12 months after ICH.
resultsFour hundred and fifty-two patients were included (mean age 74.8 years, 45.6% females). Proportion of fatal outcome at 1 week was 22.1%, at 3 months 39.2%, and at 12 months 44.9%. Median mRS score before the ICH was 1 (interquartile range [IQR] 2); for survivors at 3 months, it was 5 (IQR 3); and at 12 months, it was 3 (IQR 2). Independent predictors of severe disability (mRS of 5) or death (mRS of 6) were use of oral antithrombotic drugs (OR 2.2, 95% CI 1.3-3.8, p = 0.04), mRS score before the ICH (OR 1.8, 95% CI 1.4-2.2, p < 0.001), Glasgow Coma Scale (GCS) on admission (OR 8.3, 95% CI 3.5-19.7, p < 0.001), hematoma volume >60 ml (OR 4.5, 05% CI 2.0-10.2, p < 0.001), and intraventricular hematoma extension (OR 1.8, 95% CI 0.8-4.2, p < 0.001).
conclusionIntracerebral hemorrhage is associated with high mortality, and more than one third of survivors end up with severe disability or death 3 months later. Predictors of severe disability or death were use of oral antithrombotic drugs, functional disability prior to ICH, low GCS on admission, larger hematoma volume, and intraventricular hematoma extension.
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