ArticleAmerican journal of epidemiology2019
Maternal Smoking During Pregnancy and Timing of Puberty in Sons and Daughters: A Population-Based Cohort Study.
Article in American journal of epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 77 citations in OpenAlex.
- Pubertal timing and tempo and body mass index trajectories: investigating the confounding role of childhood body mass index.American journal of epidemiology · 2025Article
- Maternal time interval between menarche and childbirth is associated with daughter's age at menarche.Acta obstetricia et gynecologica Scandinavica · 2025Article
- Atopic dermatitis in childhood and pubertal development: A nationwide cohort study.JAAD international · 2025Article
- Understanding Susceptibility to Breast Cancer: From Risk Factors to Prevention Strategies.International journal of molecular sciences · 2025Review
- Timing and tempo of pubertal development and substance use in adolescence: a cohort study in the Danish National Birth Cohort.Human reproduction open · 2025Article
- Prenatal, newborn and childhood factors and the timing of puberty in boys and girls.Pediatric research · 2024Article
- Adherence to different forms of plant-based diets and pregnancy outcomes in the Danish National Birth Cohort: A prospective observational study.Acta obstetricia et gynecologica Scandinavica · 2024Observational
- FTO-mediated mCommunications biology · 2023Article
- Prenatal tobacco exposure on brain morphometry partially mediated poor cognitive performance in preadolescent children.NeuroImmune pharmacology and therapeutics · 2023Article
- Association between infant breastfeeding practices and timing of peak height velocity: A nationwide longitudinal survey in Japan.Pediatric research · 2023Article
- Pubertal timing, sex hormone levels, and associations between early life adversity and accelerated development amongst 11-year-old children of parents with schizophrenia or bipolar disorder and controls: The Danish high risk and Resilience study via 11.Comprehensive psychoneuroendocrinology · 2023Article
- The estimated effect of season and vitamin D in the first trimester on pubertal timing in girls and boys: a cohort study and an instrumental variable analysis.International journal of epidemiology · 2023Article
- Maternal Intake of Vitamin D Supplements during Pregnancy and Pubertal Timing in Children: A Population-Based Follow-Up Study.Nutrients · 2023Article
- Prenatal programming of developmental trajectories for obesity risk and early pubertal timing.Developmental psychology · 2022Article
- Puberty disorders among ART-conceived singletons: a Nordic register study from the CoNARTaS group.Human reproduction (Oxford, England) · 2022Article
- Puberty signs and its relationship with lifestyle in 8-to-10-year-old girls: A descriptive-analytical study.Journal of family medicine and primary care · 2022Article
- Timing of Pubertal Development in Boys and Girls With Congenital Heart Defects: A Nationwide Cohort Study.Journal of the American Heart Association · 2022Article
- Maternal smoking during pregnancy negatively affects brain volumes proportional to intracranial volume in adolescents born very preterm.Frontiers in human neuroscience · 2022Article
- Association of mode of delivery with offspring pubertal development in Project Viva: a prospective pre-birth cohort study in the USA.Human reproduction (Oxford, England) · 2021Article
- Early-life exposures and age at thelarche in the Sister Study cohort.Breast cancer research : BCR · 2021Article
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Because early puberty has been linked to diseases later in life, identification of modifiable causes of early puberty is of interest. We explored the possible associations between maternal smoking during pregnancy and pubertal development in sons and daughters. Between 2012 and 2017, 15,819 children from the Danish National Birth Cohort, born during 2000-2003, provided half-yearly information on puberty from the age of 11 years. We estimated adjusted age differences (in months) at attaining various pubertal milestones, including Tanner stages, per 10 daily cigarettes smoked in the first trimester of gestation. In sons, exposure to smoking in utero was associated with earlier genital development (Tanner 2, -1.3 months, 95% confidence interval (CI): -2.5, 0.0; Tanner 5, -3.7 months, 95% CI: -5.3, -2.0), pubic hair development (Tanner 2, -1.8 months, 95% CI: -2.9, -0.6; Tanner 5, -2.9 months, 95% CI: -4.2, -1.7), and voice break (-2.4 months, 95% CI: -3.6, -1.3). In daughters, maternal smoking was associated with earlier breast development (Tanner 2, -3.4 months, 95% CI: -5.3, -1.5; Tanner 5, -4.7 months, 95% CI: -6.5, -2.9), pubic hair development stages 3-5 (Tanner 5, -2.5 months, 95% CI: -4.1, -1.0), and menarche (-3.1 months, 95% CI: -4.0, -2.3). Fetal exposure to tobacco smoke might advance timing of puberty in boys and girls.
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