Evidence map›Paper›PMID 30239174›Full record

ArticleCancer medicine2018

Identification of tRNA-derived small noncoding RNAs as potential biomarkers for prediction of recurrence in triple-negative breast cancer.

Wanting Feng, Yongfei Li, Jiahui Chu, Jun Li, Yanhong Zhang, Xiaorong Ding, Ziyi Fu, Wei Li, Xiang Huang, Yongmei Yin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Unlocking the role of tRNA-derived fragments in shaping breast cancer signaling.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review
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  6. The Roles of tRNA-Derived Fragments in Cancer: Updates and Perspectives.International journal of molecular sciences · 2025
    Review
  7. Article
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  11. Article
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  14. tRNA-derived fragments in gastric cancer: Biomarkers and functions.Journal of cellular and molecular medicine · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Wanting FengDepartment of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID 0000-0002-9083-4134
Yongfei LiDepartment of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Jiahui ChuDepartment of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Jun LiDepartment of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Yanhong ZhangDepartment of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Xiaorong DingDepartment of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Ziyi FuDepartment of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Wei LiDepartment of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Xiang HuangDepartment of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Yongmei YinDepartment of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Jiangsu Province Hospital · CNHuaian First People’s Hospital · CNFuzhou General Hospital of Nanjing Military Command · CNNanjing Maternity and Child Health Care Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triple-negative breast cancer (TNBC), an intrinsic subtype of breast cancer, is characterized by aggressive pathology and shorter overall survival. Yet there is no effective therapy for these patients. Breast cancer stem cells (BCSCs) in TNBC may account for treatment failure. It is urgent to identify new therapeutic targets for TNBC. tRNA-derived small noncoding RNAs (tDRs) represent a new class of small noncoding RNAs (sncRNA), which have been reported in some human diseases and biological processes. However, there is no detailed information about the relationship between tDRs and BCSCs. In this study, a population of CD44

Indexed as

Age FactorsBiomarkers, TumorCell Line, TumorFemaleGene Expression ProfilingGene Expression Regulation, NeoplasticHumansLymphatic MetastasisMCF-7 CellsNeoplasm Recurrence, LocalNeoplastic Stem CellsRNA, Small UntranslatedRNA, TransferSequence Analysis, RNATriple Negative Breast NeoplasmsBiomarkers, TumorRNA, Small UntranslatedRNA, Transferbiomarkerstem cellstDRstriple-negative breast cancer

Identifiers

PMID30239174
PMCPMC6198211
OpenAlexW2894501980

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.