ArticleJournal of clinical laboratory analysis2019
Blood routine test is a good indicator for predicting premature rupture of membranes.
Article in Journal of clinical laboratory analysis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- The neutrophil-to-lymphocyte ratio: a marker for microbial invasion of the amniotic cavity in preterm prelabor rupture of membranes.Obstetrics & gynecology science · 2026Article
- Adding dandelion to rabbit diets: enhancing the growth performance and meat quality by altering immune competence and gut microbiota.Microbiology spectrum · 2025Article
- Interpretable machine learning model for identification and risk factor of premature rupture of membranes (PROM) and its association with nutritional inflammatory index: a retrospective study.Frontiers in medicine · 2025Article
- Development of a Novel Nomogram for Predicting Premature Rupture of Membrane in Pregnant Women With Vulvovaginal Candidiasis.Frontiers in medicine · 2021Article
- Blood routine test is a good indicator for predicting premature rupture of membranes.Journal of clinical laboratory analysis · 2019Article
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Authors and funding
5 authors.
Funding
Abstract
objectiveTo assess the value of blood routine test (blood RT) in order to predict the occurrence of premature rupture of membranes (PROM).
methodsA retrospective study was conducted to collect blood RT data from 100 cases of preterm premature rupture of membranes (pPROM), 70 cases of full-term premature rupture of membranes (fPROM), and 100 cases of full-term pregnancy (Normal). Nonparametric tests were performed for each blood routine parameter, the ROC curve was established for the parameters with significant difference, and the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), positive likelihood ratios (+LR), and negative likelihood ratios (-LR) were further calculated.
resultsThe statistical results showed that WBC, NE.%, LY.%, EO.%, BA.%, NE.#, EO.#, RBC, HGB, HCT, and NLR were significantly different between pPROM and fPROM (P < 0.05). There was a significant difference in WBC, NE.%, LY.%, NE.#, MO.#, RBC, HGB, HCT, and NLR between the pPROM and Normal groups (P < 0.05). Between the fPROM and Normal groups, only WBC was statistically significant (P < 0.05). By establishing ROC curve, the results showed that when the cutoff value of WBC was 9.63 and NEU# was 7.12, their combined detection had the best predictive value with a sensitivity of 73% and a specificity of 81%. In addition, Its PPV was 79.3%, NPV was 75%, +LR was 3.84, and -LR was 0.33.
conclusionThe patient's blood RT results can be used to predict the risk of premature rupture of membranes, and in order to improve the sensitivity and specificity, multiple parameters can be combined.
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