ArticleNeuroImage. Clinical2018
MEG resting-state oscillations and their relationship to clinical symptoms in schizophrenia.
Article in NeuroImage. Clinical, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Systematic review and meta-analysis of the effects of EEG neurofeedback combined with pharmacological treatment on the positive and negative symptoms in patients with schizophrenia.Frontiers in psychiatry · 2025Pooled it
- Abnormal spontaneous activity and rest-task shift in schizophrenia.Psychiatry and clinical neurosciences · 2025Article
- Large-scale maps of altered cortical dynamics in early-stage psychosis are related to GABAergic and glutamatergic neurotransmission.Science advances · 2025Article
- Superconducting Quantum Magnetometers for Brain Investigations.Sensors (Basel, Switzerland) · 2025Review
- Resting-state EEG and MEG gamma frequencies in schizophrenia: a systematic review and exploratory power-spectrum metanalysis.Schizophrenia (Heidelberg, Germany) · 2025Review
- A Comparative Neuroimaging Review of Repetitive Head Impacts and Mild Traumatic Brain Injury from Pediatrics to Professionals.Neurotrauma reports · 2025Review
- Applications of OPM-MEG for translational neuroscience: a perspective.Translational psychiatry · 2024Review
- Penalized canonical correlation analysis reveals a relationship between temperament traits and brain oscillations during mind wandering.Brain and behavior · 2024Article
- Neurofeedback technique for treating male schizophrenia patients with impulsive behavior: a randomized controlled study.Frontiers in psychiatry · 2024Article
- Magnetoencephalography in Psychiatry: A Perspective on Translational Research and Applications.Advances in neurobiology · 2024Review
- Atypical cortical networks in children at high-genetic risk of psychiatric and neurodevelopmental disorders.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Article
- Clustering of antipsychotic-naïve patients with schizophrenia based on functional connectivity from resting-state electroencephalography.European archives of psychiatry and clinical neuroscience · 2023Article
- Transcranial Alternating Current Stimulation (tACS) and Its Role in Schizophrenia: A Scoping Review.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2023Article
- A Brief Introduction to Magnetoencephalography (MEG) and Its Clinical Applications.Brain sciences · 2022Review
- Multiscale Weighted Permutation Entropy Analysis of Schizophrenia Magnetoencephalograms.Entropy (Basel, Switzerland) · 2022Article
- Neuroimaging in schizophrenia: A review article.Frontiers in neuroscience · 2022Review
- Altered spontaneous cortical activity predicts pain perception in individuals with cerebral palsy.Brain communications · 2022Article
- Three-year reliability of MEG resting-state oscillatory power.NeuroImage · 2021Article
- Magnetoencephalography for Schizophrenia.Neuroimaging clinics of North America · 2020Review
- Reduced parietal alpha power and psychotic symptoms: Test-retest reliability of resting-state magnetoencephalography in schizophrenia and healthy controls.Schizophrenia research · 2020Article
Corrections and comments
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Authors and funding
7 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neuroimaging studies suggest that schizophrenia is characterized by disturbances in oscillatory activity, although at present it remains unclear whether these neural abnormalities are driven by dimensions of symptomatology. Examining different subgroups of patients based on their symptomatology is thus very informative in understanding the role of neural oscillation patterns in schizophrenia. In the present study we examined whether neural oscillations in the delta, theta, alpha, beta and gamma bands correlate with positive and negative symptoms in individuals with schizophrenia (SZ) during rest. Resting-state brain activity of 39 SZ and 25 neurotypical controls was recorded using magnetoencephalography. Patients were categorized based on the severity of their positive and negative symptoms. Spectral analyses of beamformer data revealed that patients high in positive symptoms showed widespread low alpha power, and alpha power was negatively correlated with positive symptoms. In contrast, patients high in negative symptoms showed greater beta power in left hemisphere regions than those low in negative symptoms, and beta power was positively correlated with negative symptoms. We further discuss these findings and suggest that different neural mechanisms may underlie positive and negative symptoms in schizophrenia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.