ArticlePalliative & supportive care2019
A mixed methods analysis of perceived cognitive impairment in hematopoietic stem cell transplant survivors.
Article in Palliative & supportive care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Experiences of Cancer-Related Cognitive Impairment Across Cancer Types: Qualitative Systematic Review.JMIR cancer · 2025Pooled it
- Impact of Cognitive Rehabilitation on Cognitive and Functional Outcomes in Adult Cancer Survivors: A Systematic Review.Seminars in oncology nursing · 2024Pooled it
- Examining the Efficacy of Bright Light Therapy on Cognitive Function in Hematopoietic Stem Cell Transplant Survivors.Journal of biological rhythms · 2022Trial
- Severe Brain Atrophy after Allogeneic Hematopoietic Stem Cell Transplantation in a Patient Suffering from Chronic Graft-versus-host Disease.Internal medicine (Tokyo, Japan) · 2026Article
- Long-Term Cognitive Outcomes in Adult Patients Receiving Chimeric Antigen Receptor T-Cell Therapies.Transplantation and cellular therapy · 2025Article
- Biological and psychological predictors of cognitive function in breast cancer patients before surgery.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Patient-reported cognitive function among hematopoietic stem cell transplant and cellular therapy patients: a scoping review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
- Remote assessment of cognitive dysfunction in hematologic malignancies using web-based neuropsychological testing.Cancer medicine · 2023Article
- Change in Patients' Perceived Cognition Following Chimeric Antigen Receptor T-Cell Therapy for Lymphoma.Transplantation and cellular therapy · 2022Article
- Cancer-related cognitive impairment is associated with perturbations in inflammatory pathways.Cytokine · 2021Article
- Psychosocial aspects of hematopoietic stem cell transplantation.World journal of transplantation · 2021Review
- Computerized cognitive training in post-treatment hematological cancer survivors: a feasibility study.Pilot and feasibility studies · 2021Article
- Understanding the Process and Challenges for Return-to-Work Post-Hematopoietic Cell Transplantation from a Musculoskeletal Perspective: A Narrative Review.Occupational therapy international · 2021Review
- Identification of the Knowledge Structure of Cancer Survivors' Return to Work and Quality of Life: A Text Network Analysis.International journal of environmental research and public health · 2020Article
- Symptoms of Survivors of Pediatric Hematopoietic Stem Cell Transplant by Age, Sex, and Transplant Type.Journal of pediatric hematology/oncology nursingArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
objectiveHematopoietic stem cell transplant (HSCT) survivors may show evidence of objective cognitive impairment; however, perceived cognitive problems and their impact on quality of life are less well-understood. The purpose of this study was to explore HSCT survivors' perceptions of cognitive impairment and its effect on daily life functioning.
methodSixty-nine autologous and allogeneic HSCT survivors nine months to three years posttransplant experiencing mild survivorship problems completed a brief structured interview regarding perceived cognitive impairment since transplant. Data were coded and content analyzed. The frequency of participants reporting cognitive problems by domain and associations between reports of cognitive problems and age, depressed mood, anxiety, and health-related quality of life were examined.
resultOverall, 49 of the 69 participants (71%) reported cognitive impairments after transplant: 38 in memory (55%), 29 in attention and concentration (42%), and smaller numbers in other domains. There were no significant differences in problems reported by transplant type. Of the 50 participants who worked before transplant, 19 (38%) did not return to work following transplant, with 12 citing cognitive and health problems as being the reason. There were significant associations between reports of cognitive impairment and younger age (p = 0.02), depressed mood (p = 0.02), anxiety (p = 0.002), and health-related quality of life (p = 0.008). SIGNIFICANCE OF
resultsA large proportion of survivors reported cognitive impairment following HSCT that impaired daily life functioning. Perceived cognitive impairment was associated with younger age, greater distress and reduced health-related quality of life.
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