Observational studyActa paediatrica (Oslo, Norway : 1992)2019
Validation of the diagnosis of necrotising enterocolitis in a Swedish population-based observational study.
Observational study in Acta paediatrica (Oslo, Norway : 1992), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Definitions of neonatal Necrotizing Enterocolitis (NEC) in randomised controlled trials: a systematic review.Journal of perinatology : official journal of the California Perinatal Association · 2026Review
- When It Is Not NEC: Recognizing Mimics of Necrotizing Enterocolitis in Preterm Infants.Children (Basel, Switzerland) · 2026Review
- Necrotizing enterocolitis.Nature reviews. Disease primers · 2026Review
- Early enteral nutrition practices and their association with growth and necrotising enterocolitis in extremely preterm infants-A dual national cohort study.Pediatric research · 2026Article
- Necrotizing Enterocolitis: A Comprehensive Review on Toll-like Receptor 4-Mediated Pathophysiology, Clinical, and Therapeutic Insights.Biomedicines · 2025Review
- Fresh Hemorrhages in Intestinal Resection Margins Are Associated with Unfavorable Clinical Outcomes in Preterm Infants with Necrotizing Enterocolitis with Surgical Intervention.Life (Basel, Switzerland) · 2024Article
- A Multifunctional, Low Cost and Sustainable Neonatal Database System.Children (Basel, Switzerland) · 2024Article
- Necrotizing enterocolitis: current understanding of the prevention and management.Pediatric surgery international · 2024Review
- Factors associated with the increased incidence of necrotising enterocolitis in extremely preterm infants in Sweden between two population-based national cohorts (2004-2007 vs 2014-2016).Archives of disease in childhood. Fetal and neonatal edition · 2023Article
- Impact of Delayed Time to Antibiotics in Medical and Surgical Necrotizing Enterocolitis.Children (Basel, Switzerland) · 2023Article
- Neonatal Morbidities and Feeding Tolerance Outcomes in Very Preterm Infants, before and after Introduction of Probiotic Supplementation.Nutrients · 2022Article
- Fecal amine metabolite analysis before onset of severe necrotizing enterocolitis in preterm infants: a prospective case-control study.Scientific reports · 2022Article
- Spontaneous intestinal perforation (SIP) will soon become the most common form of surgical bowel disease in the extremely low birth weight (ELBW) infant.Journal of perinatology : official journal of the California Perinatal Association · 2022Review
- Neonatal necrotizing enterocolitis: a case series examining clinical diagnosis with discrepant versus concordant autopsy results.Journal of perinatology : official journal of the California Perinatal Association · 2020Article
- Probiotics for Prevention of Severe Necrotizing Enterocolitis: Experience of New Zealand Neonatal Intensive Care Units.Frontiers in pediatrics · 2020Article
- Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
aimThe definition of necrotising enterocolitis (NEC) is based on clinical and radiological signs that can be difficult to interpret. The aim of the present study was to validate the incidence of NEC in the Extremely Preterm Infants in Sweden Study (EXPRESS)
methodsThe EXPRESS study consisted of all 707 infants born before 27 + 0 gestational weeks during the years 2004-2007 in Sweden. Of these infants, 38 were recorded as having NEC of Bell stage II or higher. Hospital records were obtained for these infants. Furthermore, to identify missed cases, all infants with a sudden reduction of enteral nutrition, in the EXPRESS study were identified (n = 71). Hospital records for these infants were obtained. Thus, 108 hospital records were obtained and scored independently by two neonatologists for NEC.
resultsOf 38 NEC cases in the EXPRESS study, 26 were classified as NEC after validation. Four cases not recorded in the EXPRESS study were found. The incidence of NEC decreased from 6.3% to 4.3%.
conclusionValidation of the incidence of NEC revealed over- and underestimation of NEC in the EXPRESS study despite carefully collected data. Similar problems may occur in other national data sets or quality registers.
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