Evidence map›Paper›PMID 30238428›Full record

Observational studyJournal of bone and mineral metabolism2019

Assessment of patient-reported outcomes (PROs): treatment satisfaction, medication adherence, and quality of life (QoL) and the associated factors in postmenopausal osteoporosis (PMO) patients in Korea.

Dong Won Byun, Seong-Hwan Moon, Tak Kim, Hae-Hyeog Lee, Hyoung Moo Park, Moo-Il Kang, Yong-Chan Ha, Ho-Yeon Chung, Byung-Koo Yoon, Tae-Young Kim and 21 more

Open access · greenAbstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Journal of bone and mineral metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
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  4. Article
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  6. Observational
  7. A quinoxaline-based compound ameliorates bone loss in ovariectomized mice.Experimental biology and medicine (Maywood, N.J.) · 2021
    Article
  8. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors at 20 institutions in 1 country.

Dong Won ByunDepartment of Endocrinology, Internal Medicine, Soon Chun Hyang University Hospital, Seoul, South Korea.
Seong-Hwan MoonDepartment of Orthopedic Surgery, Severance Hospital, Yonsei University Health System, Seoul, South Korea.
Tak KimDepartment of Obstetrics and Gynecology, Korea University Anam Hospital, Korea University College of Medicine, Seoul, South Korea.
Hae-Hyeog LeeDepartment of Obstetrics and Gynecology, Soonchunhyang University Bucheon Hospital, Bucheon, South Korea.
Hyoung Moo ParkDepartment of Obstetrics and Gynecology, Chung-Ang University Hospital, Seoul, South Korea.
Moo-Il KangDivision of Endocrinology and Metabolism, Department of Internal Medicine, Seoul St. Mary's Hospital, Seoul, South Korea.
Yong-Chan HaDepartment of Orthopedic Surgery, Chung-Ang University Hospital, Seoul, South Korea.
Ho-Yeon ChungDepartment of Endocrinology and Metabolism, Kyung Hee University, School of Medicine, Seoul, South Korea.
Byung-Koo YoonDepartment of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University, Seoul, South Korea.
Tae-Young KimDepartment of Orthopedic Surgery, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, South Korea.
Soo Uk ChaeDepartment of Orthopedic Surgery, Gunsan Medical Center of Wonkwang University Hospital, Gunsan, South Korea.
Chan Soo ShinDepartment of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.
Kyu-Hyun YangDepartment of Orthopedic Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea.
Jae Hyup LeeDepartment of Orthopedic Surgery, Seoul National University College of Medicine, SMG-SNU Boramae Medical Center, Seoul, South Korea.
Jae Suk ChangDepartment of Orthopedic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Sung Hoon KimDepartment of Obstetrics and Gynecology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
In Joo KimDivision of Endocrinology and Metabolism, Department of Internal Medicine, Pusan National University Hospital, Busan, South Korea.
Jung-Min KohDivision of Endocrinology and Metabolism, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Jung Hwa JungDepartment of Internal Medicine, Gyeongsang National University Hospital, Gyeongsang National University School of Medicine, Jinju, South Korea.
Kyong Wook YiDepartment of Obstetrics and Gynecology, Korea University College of Medicine, Korea University Ansan Hospital, Ansan, South Korea.
Jeong Joon YooDepartment of Orthopedic Surgery, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, South Korea.
Dong Jin ChungDepartment of Internal Medicine, Chonnam National University Medical School, Gwangju, South Korea.
Young-Kyun LeeDepartment of Orthopedic Surgery, Seoul National University Bundang Hospital, Seongnam, South Korea.
Hyun-Koo YoonDivision of Endocrinology and Metabolism, Department of Medicine, Cheil General Hospital and Women's Healthcare Center, Dankook University, Seoul, South Korea.
Seongbin HongDivision of Endocrinology and Metabolism, Department of Internal Medicine, Inha University Hospital, Inha University School of Medicine, Incheon, South Korea.
Deog-Yoon KimDepartment of Nuclear Medicine, Kyung Hee University, School of Medicine, Seoul, South Korea.
Ki Hyun BaekDivision of Endocrinology and Metabolism, Department of Internal Medicine, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Hyun-Joo KimPfizer Pharmaceuticals Korea Limited, Seoul, Republic of Korea.
Young-Joo KimPfizer Pharmaceuticals Korea Limited, Seoul, Republic of Korea.
Seongsik KangPfizer Pharmaceuticals Korea Limited, Seoul, Republic of Korea.
Yong-Ki MinDivision of Endocrinology and Metabolism, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. ykmin@skku.edu.ORCID http://orcid.org/0000-0002-0329-0037
Korea Pharma (South Korea) · KRUlsan College · KRChung-Ang University Hospital · KRKorea University Medical Center · KRKyung Hee University · KRSamsung Medical Center · KRSeoul National University Hospital · KRCheil General Hospital and Women's Healthcare Center · KRChonnam National University · KRGyeongsang National University Hospital · KRInha University Hospital · KRKorea University · KRPusan National University Hospital · KRSeoul National University · KRSeoul National University Bundang Hospital · KRSeverance Hospital · KRSoonchunhyang University · KRThe Catholic University of Korea Seoul St. Mary's Hospital · KRThe Catholic University of Korea Yeouido St. Mary's Hospital · KRWonkwang University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patient-reported outcomes (PROs) provide practical guides for treatment; however, studies that have evaluated PROs of women in Korea with postmenopausal osteoporosis (PMO) are lacking. This cross-sectional, multi-center (29 nationwide hospitals) study, performed from March 2013 to July 2014, aimed to assess PROs related to treatment satisfaction, medication adherence, and quality of life (QoL) in Korean PMO women using osteoporosis medication for prevention/treatment. Patient demographics, clinical characteristics, treatment patterns, PROs, and experience using medication were collected. The 14-item Treatment Satisfaction Questionnaire for Medication (TSQM) (score-range, 0-100; domains: effectiveness, side effects, convenience, global satisfaction), Osteoporosis-Specific Morisky Medication Adherence Scale (OS-MMAS) (score-range, 0-8), and EuroQol-5 dimensions questionnaire (index score range, - 0.22 to 1.0; EuroQol visual analog scale score range, 0-100) were used. To investigate factors associated with PROs, linear (treatment satisfaction/QoL) or logistic (medication adherence) regression analyses were conducted. A total of 1804 patients (age, 62 years) were investigated; 60.1% used bisphosphonate, with the majority (67.2%) using weekly medication, 27.8% used daily hormone replacement therapy, and 12.1% used daily selective estrogen receptor modulator. Several patients reported gastrointestinal (GI) events (31.6%) and dental visits due to problems (24.1%) while using medication. Factors associated with the highest OS-MMAS domain scores were convenience and global satisfaction. GI events were associated with non-adherence. TSQM scores for effectiveness, side effects, and GI risk factors were significantly associated with QoL. Our study elaborately assessed the factors associated with PROs of Korean PMO women. Based on our findings, appropriate treatment-related adjustments such as frequency/choice of medications and GI risk management may improve PROs.

Indexed as

Drug MonitoringPatient Reported Outcome MeasuresPatient SatisfactionQuality of LifeBone Density Conservation AgentsCross-Sectional StudiesDiphosphonatesFemaleHumansMiddle AgedOsteoporosis, PostmenopausalRepublic of KoreaSurveys and QuestionnairesTreatment OutcomeBone Density Conservation AgentsDiphosphonatesGastrointestinal eventsMedication adherencePostmenopausal osteoporosisQuality of lifeTreatment satisfaction

Identifiers

PMID30238428
OpenAlexW2890441806

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.