Evidence map›Paper›PMID 30238416›Full record

SynthesisClinical oral investigations2018

Micro-invasive interventions for managing non-cavitated proximal caries of different depths: a systematic review and meta-analysis.

Yuee Liang, Zilong Deng, Xingzhu Dai, Jinhui Tian, Wanghong Zhao

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Clinical oral investigations, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  5. Review
  6. Article
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  13. A retrospective clinical study on the resin infiltration of proximal caries lesions: the operator's effect.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2021
    Article
  14. Article
  15. Article
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  18. The revolutionary evolution in carious lesion management.Journal of conservative dentistry : JCD
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuee LiangDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Zilong DengDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Xingzhu DaiDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Jinhui TianEvidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, Gansu, China.
Wanghong ZhaoDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China. zhaowh@smu.edu.cn.

Funding

the Science and Technology Program of Guangzhou, China 201804010419the Science and Technology Program of Shenzhen, China JCYJ20160428142231354
6 · The paper itself

Abstract

objectivesThe aim of this study was to further evaluate the caries-arresting effectiveness of micro-invasive interventions for non-cavitated proximal caries and analyze their efficacy for caries lesions of different depths. MATERIALS AND

methodsRandomized clinical trials (RCTs) of micro-invasive interventions for non-cavitated proximal caries were included in this study. We searched the Cochrane Library, PubMed, Embase, and Web of Science on May 25, 2017, without restrictions. After duplicate study selection, data extraction, and risk of bias assessment, a meta-analysis of the odds ratios (OR) with 95% confidence intervals (95% CIs) and a publication bias analysis were conducted using Stata 12.0.

resultsAfter 2195 citations were screened, 8 citations of seven studies with follow-up periods from 12 to 36 months were included. The subgroup analysis showed that resin infiltration and resin sealant, but not glass ionomer cement (GIC), could reduce the caries progression rate (resin infiltration: OR = 0.15, 95% CI 0.09 to 0.24; resin sealant: OR = 0.33, 95% CI 0.19 to 0.58; GIC: OR = 0.13, 95% CI 0.01 to 2.65). Further analysis of their efficacies for caries lesions of different depths indicated that resin infiltration could arrest progression of enamel caries and caries around the enamel-dentin junction (EDJ) (enamel: OR = 0.05, 95% CI 0.01 to 0.35; EDJ: OR = 0.07, 95% CI 0.01 to 0.70). However, when the outer third of the dentin was involved, resin infiltration yielded significantly different results compared with the control group (OR = 0.42, 95% CI 0.16 to 1.10). Resin sealant seemed to be ineffective regardless of the caries depth (enamel: OR = 0.62, 95% CI 0.13 to 3.00; EDJ: OR = 0.44, 95% CI 0.09 to 2.15; dentin: OR = 0.43, 95% CI 0.07 to 2.63).

conclusionsResin infiltration is effective in arresting the progression of non-cavitated proximal caries involved in EDJ, while the therapeutic effects of resin sealant for different caries depths still needs to be further confirmed. CLINICAL RELEVANCE: Based on existing evidence, dentists should carefully select appropriate micro-invasive interventions according to the different depths of non-cavitated proximal caries.

Indexed as

Dental CariesHumansPit and Fissure SealantsRandomized Controlled Trials as TopicPit and Fissure SealantsMeta-analysisMicro-invasive interventionsNon-cavitated proximal cariesResin infiltrationResin sealantSystematic review

Identifiers

PMID30238416

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.