Evidence map›Paper›PMID 30238392›Full record

ArticleMolecular diversity2019

Design and synthesis of novel 6-substituted quinazoline-2-thiols.

Satya Karuna Pulakhandam, Naresh Kumar Katari, Sreekantha B Jonnalagadda

Abstract read
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In one paragraph

Article in Molecular diversity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Satya Karuna PulakhandamJawaharlal Nehru Technological University Kakinada, Kakinada, Andhra Pradesh, 533 003, India.
Naresh Kumar KatariDepartment of Chemistry, GITAM School of Technology, GITAM Deemed to be University, HTP Campus, Rudraram, Medak, Telangana, 502 329, India. dr.n.k.katari@gmail.com.
Sreekantha B JonnalagaddaSchool of Chemistry and Physics, University of KwaZulu-Natal, P Bag X 54001, Durban, 4000, South Africa. jonnalagaddas@ukzn.ac.za.ORCID http://orcid.org/0000-0001-6501-8875
GITAM University · INJawaharlal Nehru Technological University, Kakinada · INUniversity of KwaZulu-Natal · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel design and efficient protocol for the synthesis of new class of 6-substituted quinazoline-2-thiols is reported. The derivatization of the thioquinazolines is achieved in a strategic manner using 2-aminobenzylamine. The functionalization of the aniline followed by construction of the heterocyclic ring provides a facile way to synthesize these bifunctional quinazolines.

Indexed as

BenzylaminesDrug DesignQuinazolinesSulfhydryl CompoundsBenzylaminesQuinazolinesSulfhydryl Compounds2-Aminobenzylamine6-Substituted-2-thioquinazolinesAromatic substitutionBoc protectionDithiocarbamate

Identifiers

PMID30238392
OpenAlexW2892326787

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.