Evidence map›Paper›PMID 30237995›Full record

ArticleJournal of bone metabolism2018

Maintenance Dose of Vitamin D: How Much Is Enough?

Mir Sadat-Ali, Fawaz M Al-Anii, Haifa A Al-Turki, Adeebah Abdulaziz AlBadran, Sa'ad Mohammed AlShammari

Abstract read
In one paragraph

Article in Journal of bone metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mir Sadat-AliDepartment of Orthopaedic Surgery, King Fahd Hospital of the University, Imam AbdulRahman Bin Faisal University, Al-Khobar, Saudi Arabia.
Fawaz M Al-AniiDepartment of Orthopaedic Surgery, King Fahd Hospital of the University, Imam AbdulRahman Bin Faisal University, Al-Khobar, Saudi Arabia.
Haifa A Al-TurkiDepartment of Obstetrics and Gynecology, King Fahd Hospital of the University, Imam AbdulRahman Bin Faisal University, Al-Khobar, Saudi Arabia.
Adeebah Abdulaziz AlBadranDepartment of Orthopaedic Surgery, King Fahd Hospital of the University, Imam AbdulRahman Bin Faisal University, Al-Khobar, Saudi Arabia.
Sa'ad Mohammed AlShammariDepartment of Orthopaedic Surgery, King Fahd Hospital of the University, Imam AbdulRahman Bin Faisal University, Al-Khobar, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is still unclear the ideal vitamin D dosage once the deficiency and insufficiency is treated. Once deficiency was corrected we prospectively treated patients with 2,000 IU of vitamin D3 to check whether this dosage is enough to keep them above the 30 ng/mL of 25-hydroxy-vitamin D (25[OH]D).

methodsOne hundred and thirty-five Saudi Arabian men and women treatment naïve for the vitamin D deficiency and insufficiency were part of this study. History and clinical examination were done to rule out any metabolic bone disease. Weight and height was taken to calculate the body mass index (BMI). Patients who were vitamin D deficient (≥30 ng/mL), a standard treatment of 50,000 IU of vitamin D3 weekly for 3 months, a blood test for the vitamin D levels at the end of 3 months, maintenance dose of 2,000 IU of vitamin D3 for 3 months and a third blood sample after 3 months.

resultsThe data for 128 patients was available for analysis. The average age was 44.95±12.97 years with the mean BMI of 29.60±2.59 kg/m

conclusionsOur study indicates that the maintenance dose of 2,000 IU of vitamin D is not enough for patients to keep the 25(OH)D levels above 30 ng/mL.

Indexed as

CalcifediolDietary supplementsVitamin D deficiency

Identifiers

PMID30237995
PMCPMC6135651

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.