Article3 Biotech2018
Elicitation of silver nanoparticles enhanced the secondary metabolites and pharmacological activities in cell suspension cultures of bitter gourd.
Article in 3 Biotech, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 88 citations in OpenAlex.
- Silver nanoparticles enhance organogenesis, total flavonoid and anthocyanin contents inBiotechnology reports (Amsterdam, Netherlands) · 2026Article
- Nano-Elicitation Approaches for Boosting Secondary Metabolites in Medicinal Plant Cell Cultures.Plants (Basel, Switzerland) · 2025Review
- Silymarin-functionalized nanohydroxyapatite-chitosan nanocomposite: a promising biomaterial for oral health applications.BMC oral health · 2025Article
- Biofortified Calcium Phosphate Nanoparticles Elicit Secondary Metabolite Production in Carob Callus via Biosynthetic Pathway Activation.Plants (Basel, Switzerland) · 2025Article
- Synthesis methods impact silver nanoparticle properties and phenolic compound production in grapevine cell cultures.Scientific reports · 2025Article
- Microbial mediated silver nanoparticles enhance the potential of bioactive metabolites in the medicinal plantRSC advances · 2025Article
- Green Synthesized Silver Nanoparticles Induced Accumulation of Biomass and Secondary Metabolites in Hairy Roots ofInternational journal of molecular sciences · 2024Article
- Production of Polyphenolic Natural Products by Bract-Derived Tissue Cultures of Three MedicinalPlants (Basel, Switzerland) · 2024Article
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- Biotechnology and In Vitro Culture as an Alternative System for Secondary Metabolite Production.Molecules (Basel, Switzerland) · 2022Review
- Flavonoids a Bioactive Compound from Medicinal Plants and Its Therapeutic Applications.BioMed research international · 2022Review
- Salt Stress-Induced Anthocyanin Biosynthesis Genes andACS omega · 2021Article
- Nanoparticles as elicitors and harvesters of economically important secondary metabolites in higher plants: A review.IET nanobiotechnology · 2021Review
- Nanoparticles Affect the Expression Stability of Housekeeping Genes in Plant Cells.Nanotechnology, science and applications · 2020Article
- Advances in nanomaterials as novel elicitors of pharmacologically active plant specialized metabolites: current status and future outlooks.RSC advances · 2019Review
- Silver nanoparticles and silver salt (AgNOIET nanobiotechnology · 2019Article
- Alleviation ofPlants (Basel, Switzerland) · 2019Article
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study describes the influence of bio-synthesized silver nanoparticles (AgNPs) on phytochemicals and their pharmacological activities in the cell suspension cultures (CSC) of bitter gourd. To standardize the effect of sucrose, plant growth regulators, medium, AgNPs and growth kinetics for the biomass and bioactive compounds accumulation in CSC of bitter gourd. The medium comprising MS salts, sucrose (30 g/L) with 2,4-D (1.0 mg/L) and TDZ (0.1 mg/L) at 28 days of CSC was appropriate for biomass and bioactive compound accumulation. The contents of silver, malondialdehyde and hydrogen peroxide were highly elevated in AgNPs (10 mg/L)-elicited CSC when compared with non-elicited CSC. AgNPs (5 mg/L) elicited CSC extracts had significantly enhanced the production of total phenolic (3.5 ± 0.2 mg/g), and flavonoid (2.5 ± 0.06 mg/g) contents than in the control CSC extracts (2.5 ± 0.1 and 1.6 ± 0.05 mg/g). AgNPs (5 mg/L) elicited CSC showed a higher amount of flavonols (1822.37 µg/g), hydroxybenzoic (1713.40 µg/g) and hydroxycinnamic (1080.10 µg/g) acids than the control CSC (1199, 1394.42 and 944.52 µg/g, respectively). Because of these metabolic changes, the pharmacological activities (antioxidant, antidiabetic, antibacterial, antifungal and anticancer) were high in the AgNPs (5 mg/L)-elicited CSC extracts in bitter gourd. The study suggested the effectiveness of elicitation process in enhancing the accumulation of phenolic compounds and pharmacological activities. AgNPs-elicited CSC offered an effective and favorable in vitro method to improve the production of bioactive compounds for potential uses in pharmaceutical industries.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.