Evidence map›Paper›PMID 30237955›Full record

Article3 Biotech2018

Genetic variations of the Hemagglutinin gene of Pandemic Influenza A (H1N1) viruses in Assam, India during 2016.

Kimmi Sarmah, Biswajyoti Borkakoty, Kishore Sarma, Rahul Hazarika, Palash Kumar Das, Aniruddha Jakharia, Mandakini Das, Dipankar Biswas

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in 3 Biotech, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  5. Iranian journal of microbiology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Kimmi SarmahRegional Medical Research Centre, ICMR, N.E. Region, Post Box 105, Dibrugarh, Assam 786001 India.
Biswajyoti BorkakotyRegional Medical Research Centre, ICMR, N.E. Region, Post Box 105, Dibrugarh, Assam 786001 India.ORCID 0000-0002-6922-4198
Kishore SarmaRegional Medical Research Centre, ICMR, N.E. Region, Post Box 105, Dibrugarh, Assam 786001 India.
Rahul HazarikaRegional Medical Research Centre, ICMR, N.E. Region, Post Box 105, Dibrugarh, Assam 786001 India.
Palash Kumar DasRegional Medical Research Centre, ICMR, N.E. Region, Post Box 105, Dibrugarh, Assam 786001 India.
Aniruddha JakhariaRegional Medical Research Centre, ICMR, N.E. Region, Post Box 105, Dibrugarh, Assam 786001 India.
Mandakini DasRegional Medical Research Centre, ICMR, N.E. Region, Post Box 105, Dibrugarh, Assam 786001 India.
Dipankar BiswasRegional Medical Research Centre, ICMR, N.E. Region, Post Box 105, Dibrugarh, Assam 786001 India.
Regional Medical Research Centre · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since its emergence in 2009, Influenza A/H1N1pdm09 virus has evolved continuously. Marked genetic variations have occurred in the HA1 domain of the hemagglutinin gene causing the emergence of new variants. The present study genetically characterized the hemagglutinin (HA) gene of Influenza A/H1N1pdm09 strains from Assam circulating in 2016 that caused a mild outbreak without any reported mortality. Sequence analysis of the HA gene of 20 positive Assam/H1N1pdm09 strains revealed 3 mutations (K180Q, S202T, S220T) at the antigenic sites along with several other reported mutations which are in close proximity to the antigenic sites and therefore might affect the viral antigenicity. Phylogenetically, the Assam/H1N1pdm09 strains clustered into genogroup 6B. These genetic variations highlight the importance of continuous surveillance and characterization of Influenza A/H1N1pdm09 virus activity to track the genetic makeup and diversification that may affect the behavior of the virus.

Indexed as

AssamGenetic variationHemagglutininInfluenza A virusSwine flu H1N1

Identifiers

PMID30237955
PMCPMC6138005
OpenAlexW2891701417

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.