Evidence map›Paper›PMID 30237904›Full record

ArticleEFORT open reviews2018

Chronic pain after total knee arthroplasty.

Vikki Wylde, Andrew Beswick, Julie Bruce, Ashley Blom, Nicholas Howells, Rachael Gooberman-Hill

2 registry-linked trialsOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EFORT open reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 164 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
164citing papers in PubMed, 8 pooled it
19.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07589127 narecruitingnot on this mapstarted 2026, after this paper: background citation

GENicular Nerve Block in KNEE Arthroplasty - The GENKNEE Trial

TypeinterventionalSponsorHelse Møre og Romsdal HFRan2026 to 2029Enrolled70ConditionsOsteoarthritis (OA) of the Knee, Total Knee Arthroplasty, Genicular Nerve BlockArmsPreoperative genicular nerve block (GNB), Placebo nerve block
NCT07768033 nacompletednot on this mapstarted 2026, after this paper: background citation

The effect of chair-assisted yoga practice on sleep quality and pain levels in elderly individuals living in nursing homes

TypeinterventionalSponsorRüveyda BerkRan2026 to 2026Enrolled36ConditionsSleep Quality, PainArmsChair-Supported Yoga
3 · Its place in the literature

Who cites it

164 citing papers in PubMed, 8 syntheses or guidelines pooled it, 308 citations in OpenAlex.

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  15. [Observation of analgesic efficacy of liposomal bupivacaine for local infiltration anesthesia in unicompartmental knee arthroplasty: a prospective randomized controlled study].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2024
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104 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Vikki WyldeMusculoskeletal Research Unit, Bristol Medical School, University of Bristol, UK.
Andrew BeswickMusculoskeletal Research Unit, Bristol Medical School, University of Bristol, UK.
Julie BruceWarwick Clinical Trials Unit, Warwick Medical School, University of Warwick, UK.
Ashley BlomMusculoskeletal Research Unit, Bristol Medical School, University of Bristol, UK.
Nicholas HowellsNorth Bristol NHS Trust, Southmead Hospital, Bristol, UK.
Rachael Gooberman-HillMusculoskeletal Research Unit, Bristol Medical School, University of Bristol, UK.
National Institute for Health Research · GBNorth Bristol NHS Trust · GBUniversity of Bristol · GBUniversity of Warwick · GB

Funding

Department of Health RP-PG-0613-20001Medical Research Council G106/1178
6 · The paper itself

Abstract

Despite a good outcome for many patients, approximately 20% of patients experience chronic pain after total knee arthroplasty (TKA).Chronic pain after TKA can affect all dimensions of health-related quality of life, and is associated with functional limitations, pain-related distress, depression, poorer general health and social isolation.In both clinical and research settings, the approach to assessing chronic pain after TKA needs to be in-depth and multidimensional to understand the characteristics and impact of this pain. Assessment of this pain has been inadequate in the past, but there are encouraging trends for increased use of validated patient-reported outcome measures.Risk factors for chronic pain after TKA can be considered as those present before surgery, intraoperatively or in the acute postoperative period. Knowledge of risk factors is important to guide the development of interventions and to help to target care. Evaluations of preoperative interventions which optimize pain management and general health around the time of surgery are needed.The causes of chronic pain after TKA are not yet fully understood, although research interest is growing and it is evident that this pain has a multifactorial aetiology, with a wide range of possible biological, surgical and psychosocial factors that can influence pain outcomes.Treatment of chronic pain after TKA is challenging, and evaluation of combined treatments and individually targeted treatments matched to patient characteristics is advocated. To ensure that optimal care is provided to patients, the clinical- and cost-effectiveness of multidisciplinary and individualized interventions should be evaluated. Cite this article:

Indexed as

aetiologyassessmentchronic painepidemiologyimpactrisk factorstotal knee arthroplastytreatment

Identifiers

PMID30237904
PMCPMC6134884
OpenAlexW2885666148

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.