Evidence map›Paper›PMID 30237816›Full record

ArticleJournal of contemporary brachytherapy2018

Clinical and dosimetric consequences of imperfect applicator insertion in cervical cancer brachytherapy.

Bikramjit Chakrabarti, Suparna Kanti Pal, Harris Mahammad Sepai, Somapriya Basu Roy, Sanjay Kr Kar, Annesha Lahiri, Sounik Das, Amit Bala

Abstract read
In one paragraph

Article in Journal of contemporary brachytherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bikramjit ChakrabartiDepartment of Radiotherapy, Institute of Post-Graduate Medical Education and Research and Seth Sukhlal Kernani Memorial Hospital, Kolkata, India.
Suparna Kanti PalDepartment of Radiotherapy, Institute of Post-Graduate Medical Education and Research and Seth Sukhlal Kernani Memorial Hospital, Kolkata, India.
Harris Mahammad SepaiDepartment of Radiotherapy, Institute of Post-Graduate Medical Education and Research and Seth Sukhlal Kernani Memorial Hospital, Kolkata, India.
Somapriya Basu RoyDepartment of Radiotherapy, Institute of Post-Graduate Medical Education and Research and Seth Sukhlal Kernani Memorial Hospital, Kolkata, India.
Sanjay Kr KarDepartment of Radiotherapy, Institute of Post-Graduate Medical Education and Research and Seth Sukhlal Kernani Memorial Hospital, Kolkata, India.
Annesha LahiriDepartment of Radiotherapy, Institute of Post-Graduate Medical Education and Research and Seth Sukhlal Kernani Memorial Hospital, Kolkata, India.
Sounik DasDepartment of Radiotherapy, Institute of Post-Graduate Medical Education and Research and Seth Sukhlal Kernani Memorial Hospital, Kolkata, India.
Amit BalaDepartment of Radiotherapy, Institute of Post-Graduate Medical Education and Research and Seth Sukhlal Kernani Memorial Hospital, Kolkata, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study analyzes clinical consequences and dosimetric variations after imperfect brachytherapy insertions. It examines treatment decisions after such insertions in patients having difficult anatomy, which leads to good subsequent insertions with acceptable dose volume parameters. MATERIAL AND

methodsWe reviewed images of all insertions performed during last one year and sorted faulty ones out. Clinical outcome was assessed, analyzing original treatment records. Repeat three-dimensional planning using identical dose-optimization-technique compared their dosimetry. Statistical analysis using SPSS

resultsEighteen of 292 brachytherapy plans revealed imperfect insertions, including thirteen perforations (4.5%). Lack of pre-planning, obstructing mass, narrow vagina, acute anteversion of uterus, and multi-parity were significant (

conclusionsPre-planning by imaging is suggested in all cases of brachytherapy. Insertion of adequate length of tandem aligned to uterine axis is warranted for adequate tumor coverage. Whenever detected, acute anteflexion and mobile retroversion should be corrected. Tandem inserted in retroverted direction in uncorrectable retroverted uterus generates acceptable dose volume parameters. In cases with obstructive cervical mass, good subsequent insertion is possible with acceptable dose volume parameters, if planned dose can be delivered to its 60% volume.

Indexed as

applicatorbrachytherapycervical cancerdifficultdose-volumeguidelinesinsertionproblem

Identifiers

PMID30237816
PMCPMC6142650

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.