Evidence map›Paper›PMID 30237684›Full record

ArticleJournal of pharmacy & bioallied sciences

Potential Deoxycytidine Kinase Inhibitory Activity of Amaryllidaceae Alkaloids: An

Bashir A Yousef, Amina I Dirar, Mohamed Ahmed A Elbadawi, Mohamed K Awadalla, Magdi A Mohamed

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of pharmacy & bioallied sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Promising phytochemicals of traditional Indian herbal steam inhalation therapy to combat COVID-19 - An in silico study.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Bashir A YousefDepartment of Pharmacology, Faculty of Pharmacy, University of Khartoum, Khartoum, Sudan.
Amina I DirarDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Khartoum, Khartoum, Sudan.
Mohamed Ahmed A ElbadawiDepartment of Pharmacology, Faculty of Pharmacy, University of Khartoum, Khartoum, Sudan.
Mohamed K AwadallaDepartment of Pharmacology and Toxicology, College of Pharmacy, University of Hail, Hail, Saudi Arabia.
Magdi A MohamedDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Khartoum, Khartoum, Sudan.
University of Khartoum · SDNational Centre for Research · SDUniversity of Ha'il · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPlants of the Amaryllidaceae family have been under intense scrutiny for the presence of a couple of alkaloidal secondary metabolites with endued cytotoxic activity, such as pancratistatin (

aimTo explore the underlying cytotoxic molecular mechanisms of the Amaryllidaceae alkaloids ( MATERIALS AND

methodsAutoDock 4.0 software along with different

resultsDeoxycytidine kinase (dCK) (PDB: 1P60) was predicted as a potential target with fitting score of 5.574. In silico molecular docking of (

conclusionThe

Indexed as

Amaryllidaceae alkaloidscytotoxicitydeoxycytidine kinasein silico

Identifiers

PMID30237684
PMCPMC6142884
OpenAlexW2888780169

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.