Evidence map›Paper›PMID 30237538›Full record

ArticleCell death & disease2018

Taurine attenuates arsenic-induced pyroptosis and nonalcoholic steatohepatitis by inhibiting the autophagic-inflammasomal pathway.

Tianming Qiu, Pei Pei, Xiaofeng Yao, Liping Jiang, Sen Wei, Zhidong Wang, Jie Bai, Guang Yang, Ni Gao, Lei Yang and 4 more

Open access · goldAbstract read
In one paragraph

Article in Cell death & disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed, 2 pooled it
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 2 syntheses or guidelines pooled it, 173 citations in OpenAlex.

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  5. Taurine attenuatesmSystems · 2026
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23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Tianming QiuDepartment of Occupational & Environmental Health, School of Public Health, Dalian Medical University, Dalian, China.
Pei PeiDepartment of Occupational & Environmental Health, School of Public Health, Dalian Medical University, Dalian, China.
Xiaofeng YaoDepartment of Occupational & Environmental Health, School of Public Health, Dalian Medical University, Dalian, China.
Liping JiangDepartment of Occupational & Environmental Health, School of Public Health, Dalian Medical University, Dalian, China.
Sen WeiDepartment of Occupational & Environmental Health, School of Public Health, Dalian Medical University, Dalian, China.
Zhidong WangDepartment of Occupational & Environmental Health, School of Public Health, Dalian Medical University, Dalian, China.
Jie BaiDepartment of Nutrition & Food Safety, School of Public Health, Dalian Medical University, Dalian, China.
Guang YangDepartment of Nutrition & Food Safety, School of Public Health, Dalian Medical University, Dalian, China.
Ni GaoDepartment of Occupational & Environmental Health, School of Public Health, Dalian Medical University, Dalian, China.
Lei YangDepartment of Occupational & Environmental Health, School of Public Health, Dalian Medical University, Dalian, China.
Shuangyue QiDepartment of Occupational & Environmental Health, School of Public Health, Dalian Medical University, Dalian, China.
Rushan YanDepartment of Occupational & Environmental Health, School of Public Health, Dalian Medical University, Dalian, China.
Xiaofang LiuDepartment of Nutrition & Food Safety, School of Public Health, Dalian Medical University, Dalian, China.
Xiance SunDepartment of Occupational & Environmental Health, School of Public Health, Dalian Medical University, Dalian, China. sunxiance@dmu.edu.cn.
Dalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arsenic exposure causes nonalcoholic steatohepatitis (NASH). Inflammation is a key contributor to the pathology of nonalcoholic fatty liver disease (NAFLD), including NASH. However, it is unclear how arsenic induces inflammation. In mouse livers, we show that arsenic trioxide (As

Indexed as

AnimalsArsenicAutophagyCell SurvivalHep G2 CellsHumansInflammationMiceMice, Inbred C57BLMicroscopy, Electron, TransmissionNon-alcoholic Fatty Liver DiseasePyroptosisReal-Time Polymerase Chain ReactionSignal TransductionTaurineArsenicTaurine

Identifiers

PMID30237538
PMCPMC6148242
OpenAlexW2891633475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.