Evidence map›Paper›PMID 30237476›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2018

Pharmacologic treatment of infants with neonatal abstinence syndrome in community hospitals compared to academic medical centers.

Hayley Friedman, Gregory Parkinson, Hocine Tighiouart, Catherine Parkinson, David Tybor, Norma Terrin, Barry Lester, Karen Harvey-Wilkes, Jonathan M Davis

Abstract readComparative StudyMulticenter Study
PubMed Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Observational
  3. Neonatal abstinence syndrome management in California birth hospitals: results of a statewide survey.Journal of perinatology : official journal of the California Perinatal Association · 2020
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Hayley FriedmanDivision of Newborn Medicine, Tufts Medical Center, Boston, MA, USA.
Gregory ParkinsonCape Cod Health, Hyannis, MA, USA.
Hocine TighiouartThe Tufts Clinical and Translational Science Institute, Tufts University, Boston, MA, USA.
Catherine ParkinsonCape Cod Health, Hyannis, MA, USA.
David TyborSchool of Public Health, Tufts University School of Medicine, Boston, MA, USA.
Norma TerrinThe Tufts Clinical and Translational Science Institute, Tufts University, Boston, MA, USA.
Barry LesterDepartment of Pediatrics, Women and Infant's Hospital, Providence, RI, USA.
Karen Harvey-WilkesDivision of Newborn Medicine, Tufts Medical Center, Boston, MA, USA.
Jonathan M DavisDivision of Newborn Medicine, Tufts Medical Center, Boston, MA, USA. jdavis@tuftsmedicalcenter.org.
Tufts Medical Center · USTufts University · USCape Cod Healthcare · USProvidence College · US

Funding

Improving Outcome in Neonatal Abstinence SyndromeR01DA032889 · NIDA · TUFTS MEDICAL CENTER · PI DAVIS, JONATHAN M., LESTER, BARRY M. · 2012 to 2015
$2.8M
Establishing Risk in Neonatal Abstinence SyndromeR21DA041706 · NIDA · TUFTS MEDICAL CENTER · PI DAVIS, JONATHAN M., LESTER, BARRY M. · 2016 to 2017
$524k
NIDA NIH HHS R01 DA032889NIDA NIH HHS R21 DA041706
6 · The paper itself

Abstract

objectiveTo compare length of hospital stay (LOS), LOS due to neonatal abstinence syndrome (NAS), and duration of pharmacologic treatment in community or academic settings. STUDY

designOne hundred-two infants exposed to opioids in utero at two community hospitals were compared to 256 from eight academic centers. All infants were managed with non-pharmacologic care followed by similar pharmacologic treatment options.

resultsTwo hundred-twelve infants received pharmacologic treatment for NAS. Mean LOS (24.7 ± 8.5 vs. 24.5 ± 11.3 days), LOS due to NAS (24.0 ± 8.2 vs. 23.3 ± 9.2 days), and duration of NAS treatment (19.3 ± 8.0 vs. 18.9 ± 9.2 days) were similar in community compared to academic medical centers.

conclusionsNo significant differences were found in infants managed in the community compared to academic care settings. These findings support caring for opioid-exposed infants in both community and academic settings with the use of standardized care protocols.

Indexed as

Academic Medical CentersDelivery of Health CareFemaleHospitals, CommunityHumansInfantInfant, NewbornLength of StayLogistic ModelsMaleNeonatal Abstinence SyndromeOpiate Substitution TreatmentTreatment OutcomeUnited States

Identifiers

PMID30237476
OpenAlexW2891212172

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.