Evidence map›Paper›PMID 30237270›Full record

ArticleHaematologica2019

Somatic mosaicisms of chromosome 1 at two different stages of ontogenetic development detected by Rh blood group discrepancies.

Eva-Maria Dauber, Wolfgang R Mayr, Hein Hustinx, Marlies Schönbacher, Holger Budde, Tobias J Legler, Margit König, Oskar A Haas, Gerhard Fritsch, Günther F Körmöczi

Open access · goldAbstract read
In one paragraph

Article in Haematologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Transfusion support for a woman withImmunohematology · 2022
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Eva-Maria DauberDepartment of Blood Group Serology and Transfusion Medicine, Medical University of Vienna, Austria.
Wolfgang R MayrDepartment of Blood Group Serology and Transfusion Medicine, Medical University of Vienna, Austria.
Hein HustinxBlood Transfusion Service, Swiss Red Cross (SRK), Bern, Switzerland.
Marlies SchönbacherDepartment of Blood Group Serology and Transfusion Medicine, Medical University of Vienna, Austria.
Holger BuddeDepartment of Transfusion Medicine, University of Göttingen, Germany.
Tobias J LeglerDepartment of Transfusion Medicine, University of Göttingen, Germany.
Margit KönigChildren's Cancer Research Institute, St. Anna Hospital, Vienna, Austria.
Oskar A HaasChildren's Cancer Research Institute, St. Anna Hospital, Vienna, Austria.
Gerhard FritschChildren's Cancer Research Institute, St. Anna Hospital, Vienna, Austria.
Günther F KörmöcziDepartment of Blood Group Serology and Transfusion Medicine, Medical University of Vienna, Austria guenther.koermoeczi@meduniwien.ac.at.
Medical University of Vienna · ATSt Anna Children's Hospital · ATUniversity of Göttingen · DESwiss Red Cross · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spontaneous Rh blood group changes are a striking sign, reported to occur mainly in patients with hematologic disorders. Upon routine blood grouping, 2 unrelated individuals showed unexplained mixed red cell phenotype regarding the highly immunogenic c antigen (RH4), clinically relevant for blood transfusion and fetomaternal incompatibility. About half of their red cells were c-positive, whereas the other half were c-negative. These apparently hematologically healthy females had no history of transfusion or transplantation, and they tested negative for chimerism. Genotyping of flanking chromosome 1 microsatellites in blood, finger nails, hair, leukocyte subpopulations, and erythroid progenitor cells showed partial loss of heterozygosity encompassing the

Indexed as

Chromosomes, Human, Pair 1MosaicismAdultAgedCell Transformation, NeoplasticFemaleFlow CytometryGenotypeHematopoietic Stem Cell TransplantationHumansIn Situ Hybridization, FluorescenceLoss of HeterozygosityMicrosatellite RepeatsMyeloid CellsPhenotypeRh-Hr Blood-Group SystemRh-Hr Blood-Group System

Identifiers

PMID30237270
PMCPMC6395338
OpenAlexW2890898897

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.