Evidence map›Paper›PMID 30237214›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2019

Synthesis and Preclinical Characterization of the PSMA-Targeted Hybrid Tracer PSMA-I&F for Nuclear and Fluorescence Imaging of Prostate Cancer.

Margret Schottelius, Alexander Wurzer, Katharina Wissmiller, Roswitha Beck, Maximilian Koch, Dimitrios Gorpas, Johannes Notni, Tessa Buckle, Matthias N van Oosterom, Katja Steiger and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it, 100 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. [European journal of nuclear medicine and molecular imaging · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Preclinical Evaluation ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  11. Review
  12. Review
  13. Article
  14. Novel astatine (European journal of nuclear medicine and molecular imaging · 2025
    Article
  15. Dual targeting PET tracer [Theranostics · 2025
    Article
  16. Review
  17. Preclinical comparison of [EJNMMI radiopharmacy and chemistry · 2024
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Margret SchotteliusChair for Pharmaceutical Radiochemistry, Technische Universität München, Garching, Germany m.schottelius@tum.de.
Alexander WurzerChair for Pharmaceutical Radiochemistry, Technische Universität München, Garching, Germany.
Katharina WissmillerChair for Pharmaceutical Radiochemistry, Technische Universität München, Garching, Germany.
Roswitha BeckChair for Pharmaceutical Radiochemistry, Technische Universität München, Garching, Germany.
Maximilian KochChair for Biological Imaging (CBI), Technische Universität München, Munich, Germany, and Institute for Biological and Medical Imaging (IBMI), Helmholtz Centre Munich, Oberschleißheim, Germany.
Dimitrios GorpasChair for Biological Imaging (CBI), Technische Universität München, Munich, Germany, and Institute for Biological and Medical Imaging (IBMI), Helmholtz Centre Munich, Oberschleißheim, Germany.
Johannes NotniChair for Pharmaceutical Radiochemistry, Technische Universität München, Garching, Germany.
Tessa BuckleInterventional Molecular Imaging Laboratory, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
Matthias N van OosteromInterventional Molecular Imaging Laboratory, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
Katja SteigerInstitute for Pathology, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany; and.
Vasilis NtziachristosChair for Biological Imaging (CBI), Technische Universität München, Munich, Germany, and Institute for Biological and Medical Imaging (IBMI), Helmholtz Centre Munich, Oberschleißheim, Germany.
Markus SchwaigerDepartment of Nuclear Medicine, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany.
Fijs W B van LeeuwenInterventional Molecular Imaging Laboratory, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
Hans-Jürgen WesterChair for Pharmaceutical Radiochemistry, Technische Universität München, Garching, Germany.
Technical University of Munich · DELeiden University Medical Center · NLKlinikum rechts der Isar · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prostate-specific membrane antigen (PSMA)-targeted radiotracers

Indexed as

AnimalsCell Line, TumorCell Transformation, NeoplasticChemistry Techniques, SyntheticGlutamate Carboxypeptidase IIHydrophobic and Hydrophilic InteractionsIsotope LabelingMaleMiceMicroscopy, FluorescenceNuclear MedicineOligopeptidesOptical ImagingProstatic NeoplasmsRadioactive TracersSurgery, Computer-AssistedGlutamate Carboxypeptidase IIOligopeptidesRadioactive Tracersfluorescencehybrid tracerintraoperative guidanceprostate cancerPSMA

Identifiers

PMID30237214
PMCPMC6354225
OpenAlexW2890462791

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.