Evidence map›Paper›PMID 30236990›Full record

ArticleVirology2018

Evolutionary pathway for the 2017 emergence of a novel highly pathogenic avian influenza A(H7N9) virus among domestic poultry in Tennessee, United States.

Lei Li, Thomas J DeLiberto, Mary L Killian, Mia K Torchetti, Xiu-Feng Wan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lei LiDepartment of Basic Sciences, College of Veterinary Medicine, Mississippi State University, MS 39762, USA.
Thomas J DeLibertoNational Wildlife Disease Program, Wildlife Services, Animal and Plant Health Inspection Service, US Department of Agriculture, Fort Collins, CO 80521, USA.
Mary L KillianNational Veterinary Services Laboratories, Veterinary Services, US Department of Agriculture, Ames, IA 50010, USA.
Mia K TorchettiNational Veterinary Services Laboratories, Veterinary Services, US Department of Agriculture, Ames, IA 50010, USA.
Xiu-Feng WanDepartment of Basic Sciences, College of Veterinary Medicine, Mississippi State University, MS 39762, USA. Electronic address: wan@cvm.msstate.edu.
Mississippi State University · USAnimal and Plant Health Inspection Service · US

Funding

Training and Mentoring Core P20GM103476 · NIGMS · UNIVERSITY OF SOUTHERN MISSISSIPPI · PI MICHAEL R GARRETT · 2012 to 2026
$60.2M
Risk Assessment of Influenza A VirusesR21AI135820 · NIAID · UNIVERSITY OF MISSOURI-COLUMBIA · PI WAN, XIUFENG HENRY · 2018 to 2019
$400k
NIAID NIH HHS R21 AI135820NIGMS NIH HHS P20 GM103476
6 · The paper itself

Abstract

In March 2017, a novel highly pathogenic avian influenza A(H7N9) virus was detected at two commercial broiler breeder facilities in Tennessee, United States. In this study, a wild bird low pathogenic avian influenza A virus, A/blue-winged teal/Wyoming/AH0099021/2016(H7N9), was shown to be the probable precursor of the novel H7N9 virus; this low pathogenic virus has eight possible progenitor genes sharing > 99% sequence identity with the novel H7N9 virus. Phylogeographic analyses showed that viral gene constellations that formed and circulated among dabbling ducks contributed to the emergence of the novel H7N9 virus. This is in contrast to the virus that caused the 2016 H7N8 outbreak, which had more genetic contributions from viruses circulating among diving ducks. Study findings support the need for ongoing wild bird surveillance to monitor circulating viruses and to understand possible evolutionary pathways of virus emergence in poultry.

Indexed as

Evolution, MolecularAnimalsAnimals, DomesticAnimals, WildBirdsGenotypeInfluenza A Virus, H7N9 SubtypeInfluenza in BirdsPhylogenySequence AlignmentTennesseeTime FactorsAvian influenza A virusDabbling duckDomestic poultryEvolutionary pathwayH7N9High pathogenic avian influenzaLow pathogenic avian influenzaPhylogenetic analysisPhylogeographic analysisWild birds

Identifiers

PMID30236990
PMCPMC6269200
OpenAlexW2891958673

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.