ArticleThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2018
Associations of Age and Gender with Negative Symptom Factors and Functioning Among Middle-Aged and Older Adults with Schizophrenia.
Article in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 23 citations in OpenAlex.
- Childhood premorbid adjustment as a marker for 20-year impairments in schizophrenia spectrum disorder: results from the OPUS study.European child & adolescent psychiatry · 2026Trial
- Risk factors for postoperative delirium in patients undergoing microvascular decompression.PloS one · 2019Trial
- Sex differences in higher-order cognition in schizophrenia and unaffected first-degree relatives: a longitudinal, family study.European archives of psychiatry and clinical neuroscience · 2026Article
- Negative Symptoms and Their Associations With Other Clinical Variables and Working Memory Across the Schizophrenia Spectrum and Bipolar Disorder.Schizophrenia bulletin open · 2024Article
- Association between cannabis use and symptom dimensions in schizophrenia spectrum disorders: an individual participant data meta-analysis on 3053 individuals.EClinicalMedicine · 2023Article
- The relations between socio-demographic information and negative symptoms, mental health, and quality of life: a latent profile analysis with psychotic patients in Kosovo.Frontiers in psychiatry · 2023Article
- Gender Differences in Clinical and Psychosocial Features Among Persons With Schizophrenia: A Mini Review.Frontiers in psychiatry · 2021Review
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3 authors at 3 institutions in 2 countries.
Funding
Abstract
objectiveGender differences in neurocognition, social skills, and negative symptoms, favoring women, have been documented among young/middle-aged adults with schizophrenia. However, gender differences have rarely been examined among older adults with schizophrenia, when decreases in circulating estrogens may impact outcomes among women.
methodsCommunity-dwelling adults (N = 242, ages 40-85) with schizophrenia/schizoaffective disorder completed assessments of negative symptoms (expressive and experiential deficits), neurocognition, and social skills. Mann-Whitney U tests examined gender differences; a regression-based bootstrapped approach to moderation examined gender by age interactions.
resultsFemale participants had better neurocognition (U = 6,814.00, p = 0.011) and less severe experiential deficits (U = 4,130.50, p = 0.022). There was no gender difference in social skills (U = 5,920.50, p = 0.150). Older age was associated with greater expressive deficits among men but not women (b = -0.04; 95% confidence interval -0.0780, -0.0114; bootstrap p = 0.009).
conclusionGender differences among adults with schizophrenia may vary depending on age; gender differences in negative symptoms may vary by symptom subgroup.
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Registered trials
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