ReviewTrends in cognitive sciences2018
The Regulatory Role of the Human Mediodorsal Thalamus.
Review in Trends in cognitive sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 112 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
112 citing papers in PubMed, 1 synthesis or guideline pooled it, 211 citations in OpenAlex.
- The oxytocin system in patients with craniopharyngioma: A systematic review.Frontiers in neuroendocrinology · 2025Pooled it
- Focal tDCS of auditory cortex in chronic tinnitus: A randomized controlled mechanistic trial.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2024Trial
- Loss of Fmr1 causes subnucleus-specific decreases in dendritic complexity in mediodorsal thalamus.Brain structure & function · 2026Article
- Thalamo-cortical white matter connectivity-defined thalamic subarea volumes predict individual delay discounting.Molecular psychiatry · 2026Article
- Deficits in episodic memory and executive functions in relation to CB1 receptor availability in Parkinson's disease.Journal of Parkinson's disease · 2026Article
- Neuroinflammation-associated thalamocortical functional connectivity and cognition in older adults.Journal of neuroinflammation · 2026Article
- Electrophysiological Brain Connectivity and Subjective States Evoked by Electrical Stimulation of the Human Mid-thalamus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Network-nodal tACS induces right-lateralization of thalamocortical connectivity.Scientific reports · 2026Article
- Compromised synaptic signal from prefrontal cortex to mediodorsal thalamus in Alzheimer's disease models and its rescue by kinase inhibitors.The Journal of physiology · 2026Article
- Fmr1 knockout disrupts multiple intrinsic properties via reduced HCN channel activity in mediodorsal thalamocortical neurons.Experimental physiology · 2026Article
- Through Massage to the Brain-Neuronal and Neuroplastic Mechanisms of Massage Based on Various Neuroimaging Techniques (EEG, fMRI, and fNIRS).Journal of clinical medicine · 2026Review
- From network hub to therapeutic target: the role of mediodorsal thalamic nucleus in epilepsy.Frontiers in neuroscience · 2026Review
- Thalamocortical Structural Covariation Networks Are Related to Familial Risk for Schizophrenia in the Context of Lower Nuclei Volume Estimates in Patients: An ENIGMA Study.Biological psychiatry · 2025Article
- Progressive Changes Between Thalamic Nuclei and Cortical Networks Across Stimulus-Response Learning.Human brain mapping · 2025Article
- Shared and distinct alterations of thalamic subregional functional connectivity in early- and late-onset obsessive-compulsive disorder.Psychological medicine · 2025Article
- Brain-wide connectivity and novelty response of the dorsal endopiriform nucleus in mice.Cell reports · 2025Article
- Single pulse electrical stimulation of the medial thalamic surface induces narrower high gamma band activities in the sensorimotor cortex.Scientific reports · 2025Article
- Normative Modeling of Thalamic Nuclear Volumes and Characterization of Lateralized Volume Alterations in Alzheimer's Disease Versus Schizophrenia.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Article
- Ultra-high Field fMRI Reveals Effect of Ketamine on Vocal Processing in Common Marmosets.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- The Role of the Dorsolateral Prefrontal Cortex in Ego Dissolution and Emotional Arousal During the Psychedelic State.Human brain mapping · 2025Article
52 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 7 institutions in 4 countries.
Funding
Abstract
The function of the human mediodorsal thalamic nucleus (MD) has so far eluded a clear definition in terms of specific cognitive processes and tasks. Although it was at first proposed to play a role in long-term memory, a set of recent studies in animals and humans has revealed a more complex, and broader, role in several cognitive functions. The MD seems to play a multifaceted role in higher cognitive functions together with the prefrontal cortex and other cortical and subcortical brain areas. Specifically, we propose that the MD is involved in the regulation of cortical networks especially when the maintenance and temporal extension of persistent activity patterns in the frontal lobe areas are required.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.