ReviewJournal of the American College of Cardiology2018
Positive Pressure Ventilation in the Cardiac Intensive Care Unit.
Review in Journal of the American College of Cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07656259 (COMPARE-VENT Feasibility Pilot Study), which is not on this map. Cited by 102 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
COMPARE-VENT Feasibility Pilot Study: A Pragmatic Cluster Randomized Crossover Trial for Ventilation Strategies and Hemodynamic Impact in Critically Ill Patients With Cardiovascular Disease
Who cites it
102 citing papers in PubMed, 2 syntheses or guidelines pooled it, 235 citations in OpenAlex.
- Exploring Pandora's box: a review of thoracic compartment syndrome.Anaesthesiology intensive therapy · 2025Pooled it
- Non-invasive positive pressure ventilation (CPAP or bilevel NPPV) for cardiogenic pulmonary oedema.The Cochrane database of systematic reviews · 2019Pooled it
- Impact of CPAP and ventilator system resistance on respiratory effort in healthy volunteers.BMC pulmonary medicine · 2026Trial
- Trial
- Effect of individualized positive end-expiratory pressure titration guided by electrical impedance tomography on oxygenation in patients undergoing laparoscopic surgery in the lateral decubitus position: a randomized controlled study.Korean journal of anesthesiology · 2026Trial
- Lung perfusion estimation by saline-contrast EIT without breath hold: a randomized cross-over trial.Critical care (London, England) · 2026Trial
- Positive pressure ventilation improves oxygen saturation at altitude during recreational aviation: A pilot study.Physiological reports · 2025Trial
- Association between Respiratory Failure and Clinical Outcomes in Patients with Acute Heart Failure: Analysis of 5 Pooled Clinical Trials.Journal of cardiac failure · 2021Trial
- Trial
- Invasive ventilation and association with outcomes in heart failure-related cardiogenic shock.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Observational
- Lung-Cardiovascular Interactions and Derangements in ARDS.Comprehensive physiology · 2026Review
- Physiology-guided mechanical ventilation: Monitoring, proportional assist, and bounded automation.World journal of critical care medicine · 2026Review
- Achieving Reliable Peripheral Nerve Blockade in Cardiogenic Shock With Distorted Femoral Anatomy: A Case Report.Cureus · 2026Article
- Hemodynamic Effects of Anesthetics, Sedatives, and Analgesics in the CICU: Clinical Decision Guidance.JACC. Advances · 2026Review
- Malnutrition and Cachexia in Inpatients With Acute Cardiac Conditions: A Scientific Statement From the American Heart Association.Circulation · 2026Review
- Short-Term Physiological Effects of Moderate PEEP Levels in Invasively Ventilated Patients Without Acute or Chronic Lung Disease.Medical sciences (Basel, Switzerland) · 2026Article
- Beyond Respiratory Support: Clinical Profiles and Factors Associated with Mortality in Heart Failure Patients Admitted to the ICU.Journal of clinical medicine · 2026Article
- Role of hepatic and portal venous Doppler in constrictive pericarditis: insights from a case series.European heart journal. Case reports · 2026Article
- Article
- Aortic Valve Stenosis: Progress from Diagnosis to Treatment.Journal of clinical medicine · 2026Review
42 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 8 institutions in 2 countries.
Funding
Abstract
Contemporary cardiac intensive care units (CICUs) provide care for an aging and increasingly complex patient population. The medical complexity of this population is partly driven by an increased proportion of patients with respiratory failure needing noninvasive or invasive positive pressure ventilation (PPV). PPV often plays an important role in the management of patients with cardiogenic pulmonary edema, cardiogenic shock, or cardiac arrest, and those undergoing mechanical circulatory support. Noninvasive PPV, when appropriately applied to selected patients, may reduce the need for invasive mechanical PPV and improve survival. Invasive PPV can be lifesaving, but has both favorable and unfavorable interactions with left and right ventricular physiology and carries a risk of complications that influence CICU mortality. Effective implementation of PPV requires an understanding of the underlying cardiac and pulmonary pathophysiology. Cardiologists who practice in the CICU should be proficient with the indications, appropriate selection, potential cardiopulmonary interactions, and complications of PPV.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.