Evidence map›Paper›PMID 30236287›Full record

ArticleNeuron2018

The BDNF Val66Met Prodomain Disassembles Dendritic Spines Altering Fear Extinction Circuitry and Behavior.

Joanna I Giza, Jihye Kim, Heidi C Meyer, Agustin Anastasia, Iva Dincheva, Crystal I Zheng, Katherine Lopez, Henrietta Bains, Jianmin Yang, Clay Bracken and 4 more

Abstract readPublished Erratum
In one paragraph

Article in Neuron, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. The role of neurotrophic factors in novel, rapid psychiatric treatments.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Review
  7. Article
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Joanna I Giza
Jihye Kim
Heidi C Meyer
Agustin Anastasia
Iva Dincheva
Crystal I Zheng
Katherine Lopez
Henrietta Bains
Jianmin Yang
Clay Bracken
Conor Liston
Deqiang Jing
Barbara L Hempstead
Francis S Lee

Funding

Regulation of prefrontal cortical circuit function and reward-seeking behavior by stress-induced dendritic spine remodelingR01MH118451 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI Joshua Levitz, Conor M Liston · 2019 to 2026
$5.5M
The Impact of the BDNF Val66Met Prodomain on Cognitive Function in a Mouse Model of Alzheimer's DiseaseR01NS052819 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI HEMPSTEAD, BARBARA L, LEE, FRANCIS SANG YONG · 2005 to 2019
$5.3M
Prefrontal Cortical Microcircuit Mechanisms of Working Memory Deficits in Chronic StressR01MH109685 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI LISTON, CONOR M · 2016 to 2020
$2.8M
Acquisition of a Cold Probe and Console for a 600MHz NMR spectrometerS10OD016320 · OD · WEILL MEDICAL COLL OF CORNELL UNIV · PI BRACKEN, WILLIAM C · 2013 to 2013
$600k
Structure and Interactions of BDNFR21NS090322 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI BRACKEN, WILLIAM C · 2015 to 2016
$466k
NIH HHS S10 OD016320NIMH NIH HHS R01 MH109685NIMH NIH HHS R01 MH118451NINDS NIH HHS R01 NS052819NINDS NIH HHS R21 NS090322
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID30236287
PMCPMC6167745

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.